2824-86-4 Usage
Description
2β-(1-Hydroxy-1-methylethyl)-4-methoxy-2,3-dihydrofuro[2,3-b]quinoline is a furoquinoline alkaloid that was first isolated from Platydesma campanulata Mann and later found in Geijera salicifolia Schott. It crystallizes from C6H6-light petroleum in white needles and exhibits specific optical rotation and ultraviolet spectrum characteristics.
Uses
Used in Pharmaceutical Industry:
2β-(1-Hydroxy-1-methylethyl)-4-methoxy-2,3-dihydrofuro[2,3-b]quinoline is used as a potential therapeutic agent for various medical applications due to its unique chemical structure and properties. Its discovery in different plant sources suggests that it may have bioactive properties that can be harnessed for the development of new drugs.
Used in Chemical Research:
This furoquinoline alkaloid is used as a subject of study in chemical research to understand its structure, properties, and potential applications. The detailed description of its crystallization, optical rotation, and ultraviolet spectrum provides valuable information for scientists to explore its chemical behavior and interactions with other compounds.
Used in Natural Product Extraction:
2β-(1-Hydroxy-1-methylethyl)-4-methoxy-2,3-dihydrofuro[2,3-b]quinoline is used in the extraction and purification processes of natural products from plants like Platydesma campanulata and Geijera salicifolia. Its isolation and characterization can help in the development of efficient extraction methods and the identification of other bioactive compounds from these plant sources.
References
Werner, Schuer., Tetrahedron, 19, 1293 (1963)
Bowman, Grundon., Chem. Commun., 334 (1965)
Bowman, Grundon.,J. Chem. Soc., C, 1504 (1966)
Johns, Lamberton., Austral. J. Chem., 19,1991 (1966)
Boyd, Grunson., Tetrahedron Lett., 2637 (1967)
Check Digit Verification of cas no
The CAS Registry Mumber 2824-86-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,2 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2824-86:
(6*2)+(5*8)+(4*2)+(3*4)+(2*8)+(1*6)=94
94 % 10 = 4
So 2824-86-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H17NO3/c1-15(2,17)12-8-10-13(18-3)9-6-4-5-7-11(9)16-14(10)19-12/h4-7,12,17H,8H2,1-3H3/t12-/m1/s1
2824-86-4Relevant articles and documents
Synthesis and absolute stereochemistry assignment of enantiopure dihydrofuro- and dihydropyrano-quinoline alkaloids
Boyd, Derek R.,Sharma, Narain D.,Barr, Stephen A.,Carroll, Jonathan G.,Mackerracher, Donald,Malone, John F.
, p. 3397 - 3405 (2007/10/03)
The chiral quinoline alkaloids platydesmine 3, platydesmine methosalt 4 and edulinine 9, have been synthesised in enantiopure form via asymmetric dihydroxylation of the achiral alkaloid atanine 1. Chromatographic separation of MTPA diastereoisomers 20 formed from racemic bromohydrin derivatives of atanine 1 was a key step in the synthesis of geibalansine 7, edulinine 9, ribalinine 10, Ψ-ribalinine 11 and araliopsine 12 as single enantiomers. The absolute configurations of (+)-platydesmine methosalt 4 and (-)-Ψ-ribalinine 11 were unequivocally determined by X-ray crystallography while stereochemical correlation and circular dichroism spectroscopy methods were used to assign absolute configurations to platydesmine 3, geibalansine 7, ribalinine 10, araliopsine 12 and edulinine 9. Possible errors which earlier led to the incorrect assignment of absolute configurations of the quinoline alkaloids platydesmine 3, platydesmine methosalt 4, edulinine 9, araliopsine 12 and other related chiral quinoline alkaloids are discussed.
