28257-00-3

Basic information

• Product Name: 2,3-dihydro-1-methyl-2-phenylbenzo[d][1,3,2]diazaborinin-4(1H)-one
• Synonyms: 2,3-dihydro-1-methyl-2-phenylbenzo[d][1,3,2]diazaborinin-4(1H)-one
• CAS NO: 28257-00-3
• Molecular Weight: 236.081
• Mol File: 28257-00-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-dihydro-1-methyl-2-phenylbenzo[d][1,3,2]diazaborinin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-1-methyl-2-phenylbenzo[d][1,3,2]diazaborinin-4(1H)-one(28257-00-3)
• EPA Substance Registry System: 2,3-dihydro-1-methyl-2-phenylbenzo[d][1,3,2]diazaborinin-4(1H)-one(28257-00-3)

Safety Data

• Hazardous Substances Data: 28257-00-3(Hazardous Substances Data)

Upstream product

• 7505-81-9 2-methylaminobenzamide 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1296939-40-6 2-[2-(dimethylphenylsilyl)phenyl]-2,3-dihydro-1-methylbenzo[d][1,3,2]diazaborinin-4(1H)-one 

Relevant articles and documents

Anthranilamide: A simple, removable ortho -directing modifier for arylboronic acids serving also as a protecting group in cross-coupling Reactions

Anthranilamide (AAM) serves as a bifunctional modifier on the boron atom in catalytic transformations of arylboronic acids. It makes boronyl groups unreactive in Suzuki-Miyaura coupling and promotes Ru-catalyzed ortho-silylation. Suzuki-Miyaura coupling of AAM-modified bromophenylboronic acids with tolylboronic acid gave 1,1′-biaryl-4-boronic acid bearing AAM on the boron atom, which subsequently underwent Ru-catalyzed ortho-silylation at the 3-position by virtue of the ortho-directing effect of the AAM group.