28272-96-0

Basic information

• Product Name: 2-ethenylbenzaldehyde
• Synonyms: 2-Ethenylbenzaldehyde; Benzaldehyde, 2-ethenyl-; ETHENYLBENZALDEHYDE
• CAS NO: 28272-96-0
• Molecular Formula: C₉H₈O
• Molecular Weight: 132.1592
• Mol File: 28272-96-0.mol
• Article Data: 54

Chemical Properties

• Boiling Point: 232.5°C at 760 mmHg
• Flash Point: 111.4°C
• Density: 1.04g/cm³
• Vapor Pressure: 0.0589mmHg at 25°C
• Refractive Index: 1.607
• CAS DataBase Reference: 2-ethenylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethenylbenzaldehyde(28272-96-0)
• EPA Substance Registry System: 2-ethenylbenzaldehyde(28272-96-0)

Safety Data

• Hazardous Substances Data: 28272-96-0(Hazardous Substances Data)

Upstream product

• 75802-22-1 1-ethoxyisochromane 
• 855623-52-8 1-Butoxy-isochroman 
• 2591-86-8 N-Formylpiperidine 
• 2039-88-5 2-bromostyrene 
• 27326-44-9 methyl o-vinylbenzoate 
• 35106-82-2 2-vinylbenzylalcohol 
• 68-12-2 N,N-dimethyl-formamide 
• 3230-65-7 3,4-dihydroisoquinoline 
• 107531-56-6 (2-vinyl-phenyl)magnesium bromide 
• 69460-11-3 (1R,2R,3R,5S)-(-)-Isopinocampheylamine 
• 22901-09-3 2-(2-bromoethyl)benzaldehyde 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 20706-69-8 (1S,3S,4R)-menthylamine 
• 32511-35-6 exo-bornylamine 

Downstream Products

• 22927-13-5 2-ethylbenzaldehyde 
• 35106-82-2 2-vinylbenzylalcohol 
• 38846-62-7 o-<1,2-Dibromethyl>-benzaldehyd 
• 142819-86-1 C₁₄H₁₈⁽²⁾HNO 
• 50604-01-8 ethyl-benzoic acid methyl ester 
• 122911-57-3 2-(2-styryl)indane-1,3-dione 
• 155129-43-4 4-Methoxy-2-(2-vinyl-phenyl)-indan-1,3-dione 
• 56427-44-2 ethyl ester of ortho-ethylbenzoic acid 
• 78926-45-1 o-(trans-2,3-diphenylaziridin-1-yliminomethyl)styrene 
• 80663-40-7 4'-methyl-2-vinylstilbene 
• 75135-83-0 (E,E)-6-trimethylsilyl-1-(2-vinyl-1-phenyl)-3,5-hexadien-1-ol 
• 75135-86-3 (E)-4-trimethylsilyl-2-vinyl-1-(2-vinyl-1-phenyl)-3-buten-1-ol 
• 86486-99-9 (E)-4-(2-Trimethylsilanyl-ethyl)-1-(2-vinyl-phenyl)-hexa-3,5-dien-1-ol 
• 155129-45-6 4,9-Dimethoxy-2-(2-vinyl-phenyl)-cyclopenta[b]naphthalene-1,3-dione 

Relevant articles and documents

Construction of 4-Isochromanones through Cu(OTf)2-Catalysed Sequential C=O and C–O Bond Formation

A new strategy for the facile and efficient synthesis of 4-isochromanones has been developed. The reaction involves a Cu(OTf)2-catalysed sequential reaction of epoxides carrying electron-deficient alkenes using the solvent DMSO as the oxidant.

Diastereoselective Synthesis of the ABCD Ring System of Rubriflordilactone B

A novel nine-step diastereoselective route to the ABCD ring system of the natural product rubriflordilactone B is reported. Use of an α-substituted butenolide derived from maleic anhydride facilitated a 1,4-conjugate addition to provide a diene. The order in which a ringclosing metathesis and enolate oxidation were performed on this compound dictated the relative stereochemistry of the target. The final product exhibited anisotropic effects during roomerature NMR studies, requiring elevatederature experiments to confirm its identity.

Enantioselective synthesis of 1-aminoindene derivativesviaasymmetric Br?nsted acid catalysis

We describe a catalytic asymmetric iminium ion cyclization reaction of simple 2-alkenylbenzaldimines using a BINOL-derived chiralN-triflyl phosphoramide. The corresponding 1-aminoindenes and tetracyclic 1-aminoindanes are formed in good yields and high enantioselectivities. Further, the chemical utility of the obtained enantiopure 1-aminoindene is demonstrated for the asymmetric synthesis of (S)-rasagiline.