28332-44-7Relevant articles and documents
Engel,Schexnayder
, p. 9252 (1972)
Carbonylation of tertiary carbon radicals: synthesis of lactams
Yin, Zhiping,Zhang, Zhuan,Zhang, Youcan,Dixneuf, Pierre H.,Wu, Xiao-Feng
, p. 4655 - 4658 (2019/05/09)
Herein, we disclose an interesting iron-catalyzed approach for the carbonylation of a tertiary carbon radical. The tertiary carbon radical generated from a 1,5-hydrogen atom transfer can be captured by CO gas smoothly. Various six-membered lactams were constructed chemo-selectively in high yields.
The reaction of trialkylstannylmethyllithium with α,β-epoxy ketones and α-chloro ketones
Sato, Tadashi,Kikuchi, Toshihiro,Tsujita, Hiroshi,Kaetsu, Atsushi,Sootome, Norio,Nishida, Ken-Ichiro,Tachibana, Kazutaka,Murayama, Eigoro
, p. 3281 - 3304 (2007/10/02)
The reactions of trialkylstannylmethyllithium with α,β-epoxy ketones afforded mainly cyclopropanols, while α-chloro ketones afforded allyl alcohols and/or cyclopropanols, in varying amounts depending upon the molar ratio of the reagent to the substrate.
THE REACTION OF TRIALKYLSTANNYLMETHYLLITHIUM WITH α,β-EPOXY KETONES. A PREPARATIVE METHOD OF β,γ-UNSATURATED KETONES BY HOMOLOGATION OF α,β-UNSATURATED KETONES
Sato, Tadashi,Kikuchi, Toshihiro,Sootome, Norio,Murayama, Eigoro
, p. 2205 - 2208 (2007/10/02)
α,β-Epoxy ketones 2, upon treatment with two equivalents of trialkylstannylmethyllithium 1, afforded cyclopropanols 3 as a single product in acyclic system, and a mixture of cyclopropanols 3 and methylene 1,2-diols 4 in cyclic system.Under acidic conditions, the cyclopropanols gave β,γ-unsaturated ketones 5 in good yields.