28394-58-3Relevant articles and documents
Synthesis, spectral characterization, and biological studies of 3,5-disubstituted-1,3,4-oxadiazole-2(3H)-thione derivatives
?zyazici, Tug?e,Sahin, Fikrettin,K?ksal, Meri?
, p. 749 - 760 (2021/07/26)
The reaction of 3,4-dichlorophenyl-1,3,4-oxadiazole-2(3H)-thione with piperidine derivatives via Mannich reaction was used to generate eleven novel compounds in moderate to good yields. Synthesized molecules were characterized according to their structure
Some Novel Mannich Bases of 5-(3,4-Dichlorophenyl)-1,3,4-oxadiazole-2(3H)-one and Their Anti-Inflammatory Activity
Koksal, Meric,Ozkan-Dagliyan, Irem,Ozyazici, Tugce,Kadioglu, Beril,Sipahi, Hande,Bozkurt, Ayhan,Bilge, Suleyman S.
, (2017/09/05)
Non-steroidal anti-inflammatory drugs (NSAIDs), which are widely used for the treatment of rheumatic arthritis, pain, and many different types of inflammatory disorders, cause serious gastrointestinal (GI) side effects. The free carboxylic acid group exis
Synthesis, characterization and anti-inflammatory activity of new 5- (3,4-dichlorophenyl)-2-(aroylmethyl) thio-1,3,4-oxadiaxoles
Koksal, Meric,Bilge, S. Sirri,Bozkurt, Ayhan,Sahin, Z. Sibel,Isik, Samil,Erol, Dilek Demir
experimental part, p. 510 - 514 (2009/04/05)
Several 5-(3,4-dichlorophenyl)-2-(aroylmethyl)thio-1,3,4-oxadiazoles were synthesized and characterized by elemental analyses, IR and nuclear magnetic resonance spectra. All compounds were evaluated for anti-inflammatory activity by determining their abil