28421-56-9Relevant articles and documents
Synthesis of a New Vitamin D3 Hapten and Its Protein Conjugates
Litvinovskaya,Savachka,Sauchuk,Pradko,Mirantsova,Khripach
, p. 778 - 786 (2018)
The synthesis of 25-(1-carboxymethoxy)-imino-3(S)-hydroxy-9,10-seco-27-norcholesta-5(Z),7(E),10(19)-triene, a new hapten of vitamin D3, has been carried out in ten steps from ergosterol. The hapten was conjugated to horseradish peroxidase and bovine serum albumin. Antibodies to 25-hydroxyvitamin D3 were obtained using the synthesized conjugates. An immunochemical system was developed for the quantitative determination of 25-hydroxyvitamin D3.
Side-Chain Modified Ergosterol and Stigmasterol Derivatives as Liver X Receptor Agonists
Marinozzi, Maura,Castro Navas, Francisco Fermin,Maggioni, Daniela,Carosati, Emanuele,Bocci, Giovanni,Carloncelli, Maria,Giorgi, Gianluca,Cruciani, Gabriele,Fontana, Raffaella,Russo, Vincenzo
, p. 6548 - 6562 (2017/08/17)
A series of stigmasterol and ergosterol derivatives, characterized by the presence of oxygenated functions at C-22 and/or C-23 positions, were designed as potential liver X receptor (LXR) agonists. The absolute configuration of the newly created chiral ce
A CONVENIENT SYNTHESIS OF 1α,25-DIHYDROXY-28-NORVITAMIN-D2
Moriarty, Robert M.,Kim, Joonggon,Penmasta, Raju
, p. 3741 - 3744 (2007/10/02)
The title compound was synthesized via the Julia olefination using ring B-diene protected 3β-hydroxy-23,24-bisnorchola-5,7-diene-22-al acetate and the side-chain synthon 2-methyl-4-phenylsulfonyl-2-(tetrahydropyranyloxy)butane.Ring B-deprotection, photoly