2844-19-1Relevant articles and documents
Rhenium and technetium complexes that bind to amyloid-β plaques
Hayne, David J.,North, Andrea J.,Fodero-Tavoletti, Michelle,White, Jonathan M.,Hung, Lin W.,Rigopoulos, Angela,Mclean, Catriona A.,Adlard, Paul A.,Ackermann, Uwe,Tochon-Danguy, Henri,Villemagne, Victor L.,Barnham, Kevin J.,Donnelly, Paul S.
, p. 4933 - 4944 (2015)
Alzheimer's disease is associated with the presence of insoluble protein deposits in the brain called amyloid plaques. The major constituent of these deposits is aggregated amyloid-β peptide. Technetium-99m complexes that bind to amyloid-β plaques could p
AMYLOID BINDING AGENTS
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Page/Page column 38-39; 42, (2011/06/26)
There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including Alzheimer?s disease and other related amyloid-based neurodegenerative diseases
Convenient methods for preparing ?-conjugated linkers as building blocks for modular chemistry
Kulhanek, Jiri,Bures, Filip,Ludwig, Miroslav
scheme or table, (2010/04/22)
Simple, straightforward and optimized procedures for preparing extended ?-conjugated linkers are described. Either unsubstituted or 4-donor substituted ?-linkers bearing a styryl, biphenyl, phenylethenylphenyl, and phenylethynylphenyl ?-conjugated backbone are functionalized with boronic pinacol esters as well as with terminal acetylene moieties allowing their further use as building blocks in Suzuki-Miyaura or Sonogashira coupling reactions.