28493-86-9

Basic information

• Product Name: 4-nitrophenyl 4-{[(benzyloxy)carbonyl]amino}butanoate
• CAS NO: 28493-86-9
• Molecular Formula: C₁₈H₁₈N₂O₆
• Molecular Weight: 358.3453
• Mol File: 28493-86-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 559.2°C at 760 mmHg
• Flash Point: 292°C
• Density: 1.289g/cm³
• Vapor Pressure: 1.55E-12mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 4-nitrophenyl 4-{[(benzyloxy)carbonyl]amino}butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitrophenyl 4-{[(benzyloxy)carbonyl]amino}butanoate(28493-86-9)
• EPA Substance Registry System: 4-nitrophenyl 4-{[(benzyloxy)carbonyl]amino}butanoate(28493-86-9)

Safety Data

• Hazardous Substances Data: 28493-86-9(Hazardous Substances Data)

Upstream product

• 100-02-7 4-nitro-phenol 
• 5105-78-2 4-(benzyloxycarbonylamino)butyric acid 
• 501-53-1 benzyl chloroformate 
• 7693-46-1 4-Nitrophenyl chloroformate 

Downstream Products

• 117490-48-9 1,8-bis(N-carbobenzoxy-4-aminobutyryl)-3,3,4,4,5,5,6,6-octafluorooctanediamine 
• 117490-49-0 1,12-bis(N-carbobenzoxy-4-aminobutyryl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-hexadecafluorododecanediamine 
• 35821-20-6 γ-(carbobenzoxyamino)butyramide 
• 87880-80-6 4-aminobutyryl p-nitrophenyl ester 

Relevant articles and documents

sym-Homospermidine, a naturally occurring polyamine.

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Synthesis of functionalized glutamine- and asparagine-type peptoids-scope and limitations

N-Alkylated glycine oligomers ('peptoids') can serve as potent peptidomimetic systems. Installing different functional groups can often be a challenge, and minimizes yields and purities. Here, we describe the synthesis of different amide-containing submonomers which were obtained as free bases, as well as their incorporation into peptoids. By using the free amines, the coupling results on solid support could be improved, and various functionalized peptoids were prepared. Additionally, an interesting dimerization side reaction leading to cross-linked peptoids was observed during synthesis.