2852-68-8

Basic information

• Product Name: 3,3'-Dimethylbenzophenone
• Synonyms: 3,3'-Dimethylbenzophenone;Bis(m-tolyl) ketone
• CAS NO: 2852-68-8
• Molecular Formula: C₁₅H₁₄O
• Molecular Weight: 210.27
• Mol File: 2852-68-8.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 354.1°C at 760 mmHg
• Flash Point: 153.7°C
• Appearance: /
• Density: 1.05g/cm³
• Vapor Pressure: 3.43E-05mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: 3,3'-Dimethylbenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-Dimethylbenzophenone(2852-68-8)
• EPA Substance Registry System: 3,3'-Dimethylbenzophenone(2852-68-8)

Safety Data

• Hazardous Substances Data: 2852-68-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H14O/c1-11-5-3-7-13(9-11)15(16)14-8-4-6-12(2)10-14/h3-10H,1-2H3

Upstream product

• 858453-51-7 bis(3-methylphenyl)methanimine 
• 28987-79-3 m-tolylmagnesium bromide 
• 1711-06-4 3-Methylbenzoyl chloride 
• 591-17-3 meta-bromotoluene 
• 201230-82-2 carbon monoxide 
• 625-95-6 3-Iodotoluene 
• 2093-46-1 2-methylphenyl diazonium tetrafluoroborate 
• 937-01-9 trimethyl(3-methylphenyl)stannane 
• 456-39-3 3-chlorobenzenediazonium tetrafluoroborate 
• 1422-76-0 3-methylbenzenediazonium tetrafluoroborate 
• 74032-44-3 3-Methyl-thiobenzoic acid S-pyridin-2-yl ester 
• 67-56-1 methanol 
• 35569-54-1 Tri-m-tolyl-stibane 
• 26919-48-2 tri-m-tolylbismuth 

Downstream Products

• 51226-48-3 Tri-m-tolyl-methanol 
• 13389-72-5 bis(3-methylphenyl)methanol 
• 7367-40-0 3,3'-dimethyl-benzophenone-(2,4-dinitro-phenylhydrazone) 
• 67660-38-2 3,3'-Bis(bromomethyl)benzophenone 
• 144617-65-2 3,3-bis(3-methylphenyl)-2-propenenitrile 
• 4480-11-9 Benzophenon-dicarbonsaeure-(3,3') 
• 100200-63-3 tetrabis-(m-tolyl)-ethylene 
• 1026794-30-8 3,3-Di-m-tolyl-oxirane-2-carboxylic acid methyl ester 
• 872053-63-9 9-(di(m-tolyl)methylene)-9H-fluorene 
• 1025800-87-6 2-Hydroxy-3-methoxy-3,3-di-m-tolyl-propionic acid methyl ester 
• 112779-45-0 7-methyl-5-(3'-methylphenyl)-1-phenyl-3H-2-benzazepine 
• 112779-49-4 9-methyl-5-(3'-methylphenyl)-1-phenyl-3H-2-benzazepine 
• 144617-70-9 N-(3,3-Di-m-tolyl-allyl)-benzamide 
• 6472-69-1 benzophenone-3,3'-dicarboxylic acid chloride 

Relevant articles and documents

Palladium nanoparticles on amino-modified silica-catalyzed C–C bond formation with carbonyl insertion

Abstract: A practical and heterogeneously catalyzed Stille, homo-coupling, and Suzuki carbonylation reaction has been reported using Pd nanoparticles supported on amino-vinyl silica-functionalized magnetic carbon nanotube (CNT@Fe3O4@SiO2-Pd) for the efficient synthesis of symmetrical and unsymmetrical diaryl ketones from aryl iodides. A wide variety of symmetrical and unsymmetrical diaryl ketones were obtained in high yields under CO gas-free conditions using Mo(CO)6 as an efficient carbonyl source. Considering the atom economy of Ph3SnCl, less than an equimolar amount can be applied in Stille transformation, which is of great importance due to the toxicity of organotin derivatives. Moreover, no phosphine ligand and external reducing agent were necessary in these coupling carbonylation reactions. This heterogeneous Pd catalyst offers high activity with very low palladium leaching. Finally, the catalyst can be reused and recycled for six steps without loss in activity, exhibiting good example of sustainable methodology. Graphic abstract: [Figure not available: see fulltext.].

Method for preparing symmetric diarylketone through catalytic oxidative carbonylation

The invention discloses a method for preparing symmetric diarylketone of a formula (I) as shown in the description. The method comprises the following steps: mixing arylboronic acid (II) (Ar-B(OH)2 (II)), a palladium catalyst, a promoter and an organic solvent in a reactor, introducing air and CO having a volume ratio of (7-19):1, reacting under the conditions of a pressure of 1-6 atm and a temperature of 30-80 DEG C for 8-16 hours, and performing after-treatment on the reaction solution, thereby obtaining the product symmetric diarylketone. According to the method disclosed by the invention,the air directly serves as an oxidizing agent to replace the O2 to be applied to oxidative carbonylation of the arylboronic acid, and the ratio of the air to CO is beyond an explosion limit. Therefore, the catalytic system is safe and economic. The palladium catalyst is small in dosage and simple in separation and can be recycled for several times. The method disclosed by the invention is mild inreaction condition, excellent in substrate suitability and high in yield.

Nickel-Catalyzed Molybdenum-Promoted Carbonylative Synthesis of Benzophenones

A nickel-catalyzed molybdenum-promoted carbonylative coupling reaction for the synthesis of benzophenones from aryl iodides has been developed. Various substituted diaryl ketones were synthesized in moderate to excellent yields under CO-gas-free conditions. A synergetic effect of both nickel and molybdenum has been observed, which is also responsible for the success of this transformation.