286441-68-7

Basic information

• Product Name: 2-METHOXY-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL
• Synonyms: 2-METHOXY-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL
• CAS NO: 286441-68-7
• Molecular Formula: C₉H₉F₃O₂
• Molecular Weight: 206.17
• Mol File: 286441-68-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 241.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.282±0.06 g/cm3(Predicted)
• PKA: 14.10±0.10(Predicted)
• CAS DataBase Reference: 2-METHOXY-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL(286441-68-7)
• EPA Substance Registry System: 2-METHOXY-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL(286441-68-7)

Safety Data

• Hazardous Substances Data: 286441-68-7(Hazardous Substances Data)

Upstream product

• 286441-66-5 methyl 2-methoxy-4-(trifluoromethyl)benzoate 
• 220162-64-1 methyl 2-fluoro-4-(trifluoromethyl)benzoate 

Downstream Products

• 132927-09-4 2-methoxy-4-(trifluoromethyl)benzaldehyde 
• 1025953-97-2 (2E,4E)-5-(2-Methoxy-4-trifluoromethyl-phenyl)-penta-2,4-dienal 
• 1025993-04-7 (2E,4E)-5-(2-Methoxy-4-trifluoromethyl-phenyl)-penta-2,4-dien-1-ol 
• 1026230-08-9 (2E,4E)-5-(2-Methoxy-4-trifluoromethyl-phenyl)-penta-2,4-dienoic acid ethyl ester 

Relevant articles and documents

Discovery of (phenoxy-2-hydroxypropyl)piperidines as a novel class of voltage-gated sodium channel 1.7 inhibitors

A novel class of NaV1.7 inhibitors has been identified by high-throughput screening followed by structure activity relationship studies. Among this series of compounds, piperidine 9o showed potent human and mouse NaV1.7 inhibitory activities with fair subtype selectivity over NaV1.5. Compound 9o successfully demonstrated analgesic efficacy in mice comparable to that of the currently used drug, mexiletine, but with an expanded central nervous system safety margin.