286836-26-8

Basic information

• Product Name: acetic acid 3-broMo-4-fluoro-phenyl ester
• Synonyms: acetic acid 3-broMo-4-fluoro-phenyl ester
• CAS NO: 286836-26-8
• Molecular Formula: C8H6BrFO2
• Molecular Weight: 233.037
• Mol File: 286836-26-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: acetic acid 3-broMo-4-fluoro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid 3-broMo-4-fluoro-phenyl ester(286836-26-8)
• EPA Substance Registry System: acetic acid 3-broMo-4-fluoro-phenyl ester(286836-26-8)

Safety Data

• Hazardous Substances Data: 286836-26-8(Hazardous Substances Data)

Upstream product

• 27407-11-0 3-bromo-4-fluorophenol 
• 75-36-5 acetyl chloride 
• 1007-15-4 4-fluoro-3-bromoacetophenone 
• 937-14-4 3-chloro-benzenecarboperoxoic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 865449-63-4 1-(4-bromo-5-fluoro-2-hydroxyphenyl)ethan-1-one 
• 286836-28-0 2-allyl-3-bromo-4-fluorophenol 
• 1472652-17-7 2-allyl-4-fluoro-5-bromophenol 
• 286836-27-9 3-bromo-4-fluorophenyl allyl ether 
• 27407-11-0 3-bromo-4-fluorophenol 

Relevant articles and documents

Spiro derivative, preparation method thereof and application of spiro derivative in medicine

The invention relates to a spiro derivative, a preparation method thereof and application of the spiro derivative in medicine. Specifically, the invention relates to the spiro derivative shown in a general formula (I), the preparation method thereof, a pharmaceutical composition containing the spiro derivative and application of the spiro derivative as a therapeutic agent, especially application of the spiro derivative as an RAF inhibitor and application of the spiro derivative in preparation of drugs for treating or preventing various diseases (including cancers) related to over-expression RAF activity.

NOVEL BIPHENYL COMPOUND OR SALT THEREOF

The present invention provides a compound represented by Formula (I) or a salt thereof; an LSD1 inhibitor that contains the compound or a salt thereof as an active ingredient; a pharmaceutical composition that contains the compound or a salt thereof; and

METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1

A method for predicting a therapeutic effect of a chemotherapy using an antitumor agent comprising an LSD1 inhibitor in a cancer patient based on an expression level of INSM1 in a sample containing tumor cells isolated from the cancer patient.