28710-97-6

Basic information

• Product Name: 3-amino-1-phenyl-4,5-dihydropyrazolin-5-one
• Synonyms: 3-amino-1-phenyl-4,5-dihydropyrazolin-5-one;5-Amino-1,2-dihydro-2-phenyl-3H-pyrazol-3-one;5-Amino-2-phenyl-1,2-dihydro-3H-pyrazol-3-one;Aids026848;Aids-026848;Nsc266160;3-aMino-1-phenyl-1H-pyrazol-5-ol;5-Amino-2-phenyl-1H-pyrazol-3(2H)-one
• CAS NO: 28710-97-6
• Molecular Formula: C₉H₉N₃O
• Molecular Weight: 175.18726
• EINECS: 249-175-7
• Mol File: 28710-97-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 297.6 °C at 760 mmHg
• Flash Point: 133.8 °C
• Appearance: /
• Density: 1.294 g/cm³
• Vapor Pressure: 0.00133mmHg at 25°C
• Refractive Index: 1.635
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 3-amino-1-phenyl-4,5-dihydropyrazolin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-1-phenyl-4,5-dihydropyrazolin-5-one(28710-97-6)
• EPA Substance Registry System: 3-amino-1-phenyl-4,5-dihydropyrazolin-5-one(28710-97-6)

Safety Data

• Hazardous Substances Data: 28710-97-6(Hazardous Substances Data)

Usage

General Description

3-amino-1-phenyl-4,5-dihydropyrazolin-5-one is an organic compound that contains an amino group, a phenyl group, and a dihydropyrazolin-5-one ring structure. It is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 3-amino-1-phenyl-4,5-dihydropyrazolin-5-one has been shown to possess analgesic and anti-inflammatory properties, making it a potential candidate for the development of new drugs for pain management and inflammatory conditions. Its unique structure also makes it a valuable intermediate in the synthesis of other complex organic molecules. Additionally, it has been utilized in the development of fluorescent probes for biological imaging applications. Overall, 3-amino-1-phenyl-4,5-dihydropyrazolin-5-one is a versatile chemical with a range of potential applications in medicinal chemistry and chemical biology.

InChI:InChI=1/C9H9N3O/c10-8-6-9(13)12(11-8)7-4-2-1-3-5-7/h1-6,11H,10H2

Upstream product

• 100-63-0 phenylhydrazine 
• 81711-62-8 phenylhydrazono-succinic acid diethyl ester 
• 28710-96-5 5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 105-56-6 ethyl 2-cyanoacetate 
• 39632-87-6 ethyl 3-amino-3-ethoxypropenoate 
• 735211-22-0 3-amino-3-phenylhydrazono-propionic acid ethyl ester 

Downstream Products

• 52473-01-5 5-acetylamino-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 141987-81-7 6-Amino-3-oxo-2-phenyl-3,3a-dihydro-2H-pyrazolo[3,4-b]pyridine-5-carbonitrile 
• 141987-82-8 6-Amino-4-methyl-3-oxo-2-phenyl-3,3a-dihydro-2H-pyrazolo[3,4-b]pyridine-5-carbonitrile 
• 141987-80-6 6-Amino-3-oxo-2,4-diphenyl-3,3a-dihydro-2H-pyrazolo[3,4-b]pyridine-5-carbonitrile 
• 1207354-91-3 2-phenyl-4,6-bis(trifluoromethyl)-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one 
• 1207354-92-4 4,6-bis(perfluoroethyl)-2-phenyl-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one 

Relevant articles and documents

Synthesis, characterization and biological activity of some pyrazole-pyrazolone derivatives

SIX heterocyclic compounds were synthesized based on pyrazole and pyrazolone rings. The chemical structures of the synthesized compounds were characterized by using: elemental analysis, FTIR, 1H-NMR, 13C-NMR and Mass spectra. The compounds were evaluated for their activity against gram +ve, gram -ve bacteria and fungi. The antimicrobial assessment showed the high activity of compounds I and VI.

Possible psychopharmacological agents. Part XII - Synthesis and CNS activity of some fluorine containing 2-oxo-1-phenylpyrazolo[1,5-a]pyrimidines

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