28736-83-6

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 5-hydroxy-6-methoxy-7-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-
• CAS NO: 28736-83-6
• Molecular Formula: C30H24O6
• Molecular Weight: 480.517
• Mol File: 28736-83-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 5-hydroxy-6-methoxy-7-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 5-hydroxy-6-methoxy-7-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-(28736-83-6)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 5-hydroxy-6-methoxy-7-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-(28736-83-6)

Safety Data

• Hazardous Substances Data: 28736-83-6(Hazardous Substances Data)

Upstream product

• 1351585-69-7 5,6,7-trihydroxy-2-[4-(phenylmethoxy)phenyl]-4H-1-benzopyran-4-one 
• 1402607-40-2 9-hydroxy-2,2-diphenyl-6-[4-(phenylmethoxy)phenyl]-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one 
• 1105056-24-3 9-hydroxy-6-(4-hydroxyphenyl)-2,2-diphenyl-8H-1,3-dioxolo[4,5-g][1]benzopyran-8-one 
• 529-53-3 scutellarein 
• 27740-01-8 scutellarin 

Downstream Products

• 1447-88-7 hispidulin 
• 6601-62-3 salvigenin 
• 520-12-7 pectolinarigenin 

Relevant articles and documents

A 6-methyl Scutellarin arctigenin method for the preparation of (by machine translation)

The invention relates to the field of chemical synthesis, in particular to Chinese traditional medicine molecule Scutellarin active metabolite of preparation, the ponicidin breviscapine under the action of the strong acid hydrolysis glucuro molecules are the 4 [...], 5, 6, 7? Four hydroxy flavone, the 4 [...], 5, 6, 7? Four hydroxy flavone with bromo the presence of the acid-binding agent, generating 5,6? Dihydroxybenzonic? 4 the [...], 7? B benzyloxy flavone, then in alkaline conditions with iodomethane reaction generating 5? Hydroxy? 6? Methoxy? 4 the [...], 7? B benzyloxy flavone, the final 5? Hydroxy? 6? Methoxy? 4 the [...], 7? B benzyloxy-flavone in palladium carbon catalytic hydrogenation by debenzylation in the presence of 6? Methyl Scutellarin aglycon. The step of this invention is simple, is easy to be purified, mild condition, low cost, overall reaction yield is greater than 70%, the synthetic product has high purity, greater than 99.0%, suitable for technical production. (by machine translation)

An improved synthesis of 6-o-methyl-scutellarein through selective benzylation

An improved synthesis of 6-O-methyl-scutellarein is described. Benzyl bromide was selected to protect both the hydroxyl groups at C-4'and C-7 in scutellarein. The product was then methylated and deprotected to produce the target compound in high yield in four steps.