28748-14-3

Basic information

• Product Name: 5-benzylquinoline
• Synonyms: 5-benzylquinoline
• CAS NO: 28748-14-3
• Molecular Weight: 219.286
• Mol File: 28748-14-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-benzylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzylquinoline(28748-14-3)
• EPA Substance Registry System: 5-benzylquinoline(28748-14-3)

Safety Data

• Hazardous Substances Data: 28748-14-3(Hazardous Substances Data)

Upstream product

• 1589-82-8 phenylmagnesium bromide 
• 4964-71-0 5-bromoquinoline 
• 27049-45-2 benzyl 2-pyridyl ketone 
• 260783-80-0 N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate 
• 355386-94-6 quinolin-5-ylboronic acid 
• 103-83-3 N,N'-dimethylbenzylamine 

Relevant articles and documents

Pd-Catalyzed Alkylation of (Iso)quinolines and Arenes: 2-Acylpyridine Compounds as Alkylation Reagents

The first Pd-catalyzed alkylation of (iso)quinolines and arenes is reported. The readily available and bench-stable 2-acylpyridine compounds were used as an alkylation reagent to form the structurally versatile alkylated (iso)quinolines and arenes. The method affords a convenient pathway for the introduction of alkyl groups into organic molecules.

Nickel-catalyzed cross couplings of benzylic ammonium salts and boronic acids: Stereospecific formation of diarylethanes via C-N bond activation

We have developed a nickel-catalyzed cross coupling of benzylic ammonium triflates with aryl boronic acids to afford diarylmethanes and diarylethanes. This reaction proceeds under mild reaction conditions and with exceptional functional group tolerance. Further, it transforms branched benzylic ammonium salts to diarylethanes with excellent chirality transfer, offering a new strategy for the synthesis of highly enantioenriched diarylethanes from readily available chiral benzylic amines.