28750-77-8Relevant articles and documents
A General Synthesis of 3,5-Dihalo-2H-1,4-oxazin-2-ones from Cyanohydrins
Meerpoel, Lieven,Hoornaert, Georges
, p. 905 - 908 (2007/10/02)
In a novel approach starting from O-trimethylsilyl protected or unprotected cyanohydrins and oxalyl chloride or bromide, a series of unknown 6-substituted 3,5-dihalo-2H-1,4-oxazin-2-ones were prepared.The method was shown to be efficient for various types of cyanohydrins; however cyclization was not obtained with cyanohydrins containing bulky substituents, electron-rich aryl or heteroaryl groups.A mechanism is proposed.
Studies on antidiabetic agents. III. 5-arylthiazolidine-2,4-diones as potent aldose reductase inhibitors
Sohda,Mizuno,Imamiya,Tawada,Meguro,Kawamatsu,Yamamoto
, p. 3601 - 3616 (2007/10/02)
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