287729-00-4

Basic information

• Product Name: Carbamic acid, (1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)(phenylmethyl)-, 1,1-dimethylethyl ester
• CAS NO: 287729-00-4
• Molecular Formula: C20H20N2O4
• Molecular Weight: 352.39
• Mol File: 287729-00-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)(phenylmethyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)(phenylmethyl)-, 1,1-dimethylethyl ester(287729-00-4)
• EPA Substance Registry System: Carbamic acid, (1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)(phenylmethyl)-, 1,1-dimethylethyl ester(287729-00-4)

Safety Data

• Hazardous Substances Data: 287729-00-4(Hazardous Substances Data)

Upstream product

• 220294-77-9 N^β,N^β-[bis(tert-butoxycarbonyl)amino]phthalimide 
• 1875-48-5 N-aminophthalamide 
• 215655-64-4 1-tert-butyloxycarbonyl-2-(2'-carboxybenzoyl)-hydrazine 
• 109473-36-1 N-tert-butyloxycarbonylaminoisophthalimide 
• 85-44-9 phthalic anhydride 
• 870-46-2 t-butoxycarbonylhydrazine 
• 34387-89-8 N-(tert-butoxycarbonylamino)phthalimide 
• 100-39-0 benzyl bromide 
• 100-51-6 benzyl alcohol 

Downstream Products

• 85468-51-5 2-benzylamino-1H-isoindole-1,3(2H)-dione 
• 1073-62-7 N-benzylhydrazine hydrochloride 
• 127799-53-5 1-[(1,1-dimethylethoxy)carbonyl]-2-[(phenylmethoxy)carbonyl]-2-methylhydrazine 
• 185456-43-3 N-benzyl-N’-[(tert-butoxy)carbonyl](tert-butoxy)carbohydrazide 
• 185456-32-0 1-benzyl-1,2,2-tris(tert-butoxycarbonyl)hydrazine 
• 147688-34-4 tert-butyl 1-benzylhydrazine-1-carboxylate 

Relevant articles and documents

Original and efficient synthesis of 2:1-[α/aza]-oligomer precursors

The preparation of 2:1-[α/aza]-oligomer precursors is described via Mitsunobu and exchange of protecting groups protocols in four steps in good yields starting from N-tert-butyloxycarbonylaminophtalimide. Conformational studies showed that these building blocks further led to β-turn-like folded 2:1-[α/aza]-trimer which suggests that they are good candidates to form foldamers.

N-tert-butoxycarbonylaminophthalimide, a versatile reagent for the conversion of alcohols into alkylated tert-butylcarbazates or hydrazines via the Mitsunobu protocol

An efficient two-step method has been developed for the conversion of alcohols to substituted hydrazines. The use of N-tert- butoxycarbonylaminophthalimide as an acid partner in Mitsunobu reactions with a variety of alcohols permits the synthesis of the corresponding monoalkylated tert-butylcarbazates and hydrazines.