287980-03-4Relevant articles and documents
An efficient total synthesis of (-)-vindoline
Kobayashi, Satoshi,Ueda, Toshihiro,Fukuyama, Tohru
, p. 883 - 886 (2007/10/03)
A highly efficient total synthesis of the title compound is described. Our synthesis features a highly efficient preparation of the key intermediate 11 using our novel indole synthesis methodology. A novel amine protecting protocol by means of 2,4-dinitrobenzenesulfonamides has been developed to ensure the formation of the elusive secodine-type intermediate 15 under very mild conditions.