288087-82-1

Basic information

• Product Name: (Z)-3-Amino-4,4,4-trichloro-1-(2-hydroxy-5-methoxy-phenyl)-but-2-en-1-one
• Synonyms: (Z)-3-Amino-4,4,4-trichloro-1-(2-hydroxy-5-methoxy-phenyl)-but-2-en-1-one
• CAS NO: 288087-82-1
• Molecular Weight: 310.564
• Mol File: 288087-82-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-3-Amino-4,4,4-trichloro-1-(2-hydroxy-5-methoxy-phenyl)-but-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-Amino-4,4,4-trichloro-1-(2-hydroxy-5-methoxy-phenyl)-but-2-en-1-one(288087-82-1)
• EPA Substance Registry System: (Z)-3-Amino-4,4,4-trichloro-1-(2-hydroxy-5-methoxy-phenyl)-but-2-en-1-one(288087-82-1)

Safety Data

• Hazardous Substances Data: 288087-82-1(Hazardous Substances Data)

Upstream product

• 705-15-7 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one 
• 545-06-2 trichloroacetonitrile 

Downstream Products

• 13252-84-1 4-hydroxy-6-methoxycoumarin 

Relevant articles and documents

Condensation of 2-hydroxyacetophenones with trichloroacetonitrile as a route to 2-trichloromethylchromones and 4-hydroxycoumarins

Condensation of 2-hydroxyacetophenones with trichloroacetonitrile in the presence of N-methylanilinomagnesium bromide affords hydroxyaryl β-amino-β-trichloromethylvinyl ketones, which are converted into 2-trichloromethylchromones upon treatment with concentrated HCl. The resulting compounds react with alcoholic solutions of NH3 or KOH to form 3-amino-1-(2-hydroxyaryl)-4,4,4-trichlorobut-2-en-1-ones and 4-hydroxycoumarins, respectively.