288159-87-5Relevant articles and documents
Quantitative structure-activity relationship study of N-(3-oxo-3,4- dihydro-2H-benzol[1,4]thiazine-6-carbonyl)guanidines as potent na/h exchange inhibitors
Yamamoto, Takeshi,Hori, Manabu,Watanabe, Ikuo,Harada, Kengo,Ikeda, Shoji,Ohtaka, Hiroshi
, p. 843 - 849 (2000)
We have previously reported that N-(4-isopropyl-2,2-dimethyl-3-oxo-3,4- dihydro-2H-benzo[1,4]oxazine-6carbonyl)guanidine (4b) methanesulfonate salt (KB-R9032) is a potent and highly water-soluble Na/H exchange inhibitor. In a series of studies on Na/H exc