28837-77-6 Usage
Description
(5-methoxy-1H-indol-2-yl)-morpholin-4-yl-methanone is a complex chemical compound that features a 5-methoxy-1H-indole unit connected to a morpholine ring and a methanone group. (5-methoxy-1H-indol-2-yl)-morpholin-4-yl-methanone may hold potential in medicinal chemistry due to the combination of pharmacophores from indole and morpholine, which are known for their diverse biological activities. The presence of a methoxy group on the indole unit and the morpholine ring hint at the compound's capacity to engage with a range of biological targets, positioning it as a promising candidate for pharmaceutical research and development. However, further investigation is required to fully elucidate its properties and possible applications.
Uses
Used in Pharmaceutical Industry:
(5-methoxy-1H-indol-2-yl)-morpholin-4-yl-methanone is used as a compound of interest for medicinal chemistry research due to its unique structure and potential to interact with various biological targets. Its combination of indole and morpholine pharmacophores suggests that it may contribute to the development of new drugs targeting a range of therapeutic areas.
Further studies are necessary to explore the specific applications and mechanisms of action of (5-methoxy-1H-indol-2-yl)-morpholin-4-yl-methanone in the context of drug discovery and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 28837-77-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,8,3 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28837-77:
(7*2)+(6*8)+(5*8)+(4*3)+(3*7)+(2*7)+(1*7)=156
156 % 10 = 6
So 28837-77-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H16N2O3/c1-18-11-2-3-12-10(8-11)9-13(15-12)14(17)16-4-6-19-7-5-16/h2-3,8-9,15H,4-7H2,1H3
28837-77-6Relevant articles and documents
NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT
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Paragraph 0137-0139, (2017/06/23)
The present invention relates to a novel indene derivative, a preparation method for the same, and a pharmaceutical composition for preventing or treating retinal disease comprising the same as an active ingredient. The novel indene derivative of the present invention, the optical isomer of the same, or the pharmaceutically acceptable salts of the same have excellent inhibitory efficiency of receptor-interacting serine/threonine-protein kinase 1 (RIPK1). Therefore, the composition containing the same as an active ingredient can be effectively used as a pharmaceutical composition for preventing or treating retinal disease exemplified by retinitis pigmentosa (RP), Leber congenital amaurosis (LCA), Stargardts disease, Usher syndrome, choroideremia, rod-cone or cone-rod dystrophy, ciliopathy, mitochondrial disorders, progressive retinal atrophy, degenerative retinal diseases, age-related macular degeneration (AMD), wet AMD, dry AMD, geographical atrophy, inherited or acquired macular degeneration, retinal photoreceptor diseases, retinal pigment epithelial diseases, diabetic retinopathy, cystic macular edema, uveitis, retinal detachment, traumatic retinal injury, iatrogenic retinal injury, macular holes, macular capillarectasia, ganglion cell diseases, optic nerve diseases, glaucoma, optic neuropathy, ischemic retinal diseases, retinopathy of prematurity, occlusion of retinal vessels, inherited macroaneurysm, retinal vascular diseases, ophthalmic vascular diseases, glaucomatous retinal neurodegeneration, ischemic optic neuropathy and the like.
