288371-42-6 Usage
Description
(E)-ethyl 3-(1H-indol-7-yl)acrylate, with the molecular formula C14H13NO2, is a chemical compound that is an ester of (E)-ethyl acrylate and 7-indolecarboxylic acid. It is recognized for its unique structure and properties, which make it a valuable component in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
(E)-ethyl 3-(1H-indol-7-yl)acrylate is used as a key intermediate for the development of new drugs and pharmaceutical products. Its unique structure contributes to its potential in creating novel organic compounds with therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, (E)-ethyl 3-(1H-indol-7-yl)acrylate is used as a building block for creating a variety of complex organic compounds. Its reactivity and structural features make it a versatile component in the synthesis of specialty chemicals.
Used in Material Production:
(E)-ethyl 3-(1H-indol-7-yl)acrylate also has potential uses in the production of specialty materials, where its chemical properties can be leveraged to develop new materials with specific characteristics for various applications.
Overall, (E)-ethyl 3-(1H-indol-7-yl)acrylate is a compound of interest across multiple industries, including pharmaceuticals, organic synthesis, and material science, due to its potential in the development of innovative products and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 288371-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,3,7 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 288371-42:
(8*2)+(7*8)+(6*8)+(5*3)+(4*7)+(3*1)+(2*4)+(1*2)=176
176 % 10 = 6
So 288371-42-6 is a valid CAS Registry Number.
288371-42-6Relevant articles and documents
Sulfur-Directed C7-Selective Alkenylation of Indoles under Rhodium Catalysis
Kona, Chandrababu Naidu,Nishii, Yuji,Miura, Masahiro
, p. 6252 - 6256 (2021/08/30)
Regioselective direct functionalization of an indole benzenoid fragment has been a significant challenge because of its inherently lower reactivity. In this report, we introduce a Rh-catalyzed C7-selective alkenylation of indole derivatives using a new sulfur directing group N-SCy. A notable feature of this system is that the directing group is readily installed to the indoles and easily removed after the catalysis under mild conditions.
Palladium-catalyzed C-7 alkenylation of indolines using molecular oxygen as the sole oxidant
Yang, Dong,Mao, Shuai,Gao, Ya-Ru,Guo, Dong-Dong,Guo, Shi-Huan,Li, Bin,Wang, Yong-Qiang
, p. 23727 - 23736 (2015/04/14)
A general and efficient method for the intermolecular direct C-7-selective C-H alkenylation of indolines using palladium(ii) as the catalyst and molecular oxygen as the sole oxidant has been developed. The reaction showed complete regio- and stereoselectivity. All products were E-isomers at the C-7 position, and no Z-isomers or other position substituted products could be detected. The approach also presented an efficient route for the synthesis of C-7 alkenylated indoles.
CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE
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Page/Page column 79; 107, (2010/11/08)
Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.
