288387-15-5 Usage
Brominated derivative of indole
Indole is a heterocyclic organic compound commonly found in nature, and 4-bromo-1H-indol-5-ol is a modified version of it with a bromine atom attached.
Physical appearance
White to light yellow solid This describes the color and form of the compound when isolated.
Solubility
Insoluble in water, soluble in organic solvents This indicates the compound's ability to dissolve in different types of solvents, which is important for its applications in chemical reactions and pharmaceutical research.
Uses in organic synthesis and pharmaceutical research
4-bromo-1H-indol-5-ol is commonly used as a building block for the synthesis of various bioactive molecules and pharmaceutical compounds due to its unique molecular structure.
Presence of bromine and hydroxyl groups
These functional groups in the molecular structure contribute to the compound's versatility and reactivity, making it suitable for the synthesis of a wide range of molecules.
Potential anticancer and antimicrobial activities
Studies have shown that 4-bromo-1H-indol-5-ol exhibits these activities, making it a compound of interest in medical research for the development of new treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 288387-15-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,3,8 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 288387-15:
(8*2)+(7*8)+(6*8)+(5*3)+(4*8)+(3*7)+(2*1)+(1*5)=195
195 % 10 = 5
So 288387-15-5 is a valid CAS Registry Number.
288387-15-5Relevant articles and documents
The coumarin→indole transformation - A method for preparing 4-halo-5-hydroxyindoles from coumarins
Stoffman, Elia J. L.,Clive, Derrick. L. J.
supporting information; experimental part, p. 4862 - 4870 (2010/02/16)
Readily accessible 3-alkoxycarbonyl-6-hydroxy-5-halocoumarins can be converted into 4-halo-5-hydroxyindoles by a sequence whose essential steps are conjugate reduction or conjugate addition, decarboxylation, lactone opening with ammonia, phenolic oxygen p
