288399-90-6 Usage
Chemical compound
6-FLUORO-4-METHYLCOUMARIN-3-CARBONITRIL
Family
Coumarin
Functional groups
Fluorine atom, methyl group, carbonitrile
Uses
starting material for synthesis of pharmaceuticals, agrochemicals, fine chemicals
Biological activities
anticancer, anti-inflammatory, antimicrobial
Applications
drug discovery, development, materials science, fluorescent probe in analytical chemistry
Check Digit Verification of cas no
The CAS Registry Mumber 288399-90-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,3,9 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 288399-90:
(8*2)+(7*8)+(6*8)+(5*3)+(4*9)+(3*9)+(2*9)+(1*0)=216
216 % 10 = 6
So 288399-90-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H6FNO2/c1-6-8-4-7(12)2-3-10(8)15-11(14)9(6)5-13/h2-4H,1H3
288399-90-6Relevant articles and documents
Iridium-catalyzed direct asymmetric vinylogous allylic alkylation
Shi, Chang-Yun,Xiao, Jun-Zhao,Yin, Liang
supporting information, p. 11957 - 11960 (2018/11/02)
The catalytic asymmetric vinylogous allylic alkylation of α,β-unsaturated lactones (including coumarins) was achieved with excellent regio- and enantioselectivity. Transformations of the product were carried out by means of the versatile terminal olefin and lactone moieties. The synthetic application of the present methodology was showcased by the asymmetric synthesis of an advanced synthetic Merck intermediate toward a new drug candidate.
