2884-02-8

Basic information

• Product Name: 4-methyl-1-phenylpentan-1-ol
• Synonyms: Phenylisohexanol
• CAS NO: 2884-02-8
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.2707
• Mol File: 2884-02-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 248.043°C at 760 mmHg
• Flash Point: 111.057°C
• Density: 0.954g/cm³
• Vapor Pressure: 0.013mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: 4-methyl-1-phenylpentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1-phenylpentan-1-ol(2884-02-8)
• EPA Substance Registry System: 4-methyl-1-phenylpentan-1-ol(2884-02-8)

Safety Data

• Hazardous Substances Data: 2884-02-8(Hazardous Substances Data)

Upstream product

• 541-28-6 isopentyl iodide 
• 4548-78-1 (3-methylbutyl)magnesium bromide 
• 100-52-7 benzaldehyde 
• 7316-69-0 1-phenyl-4-methyl-2-penten-1-one 
• 2050-07-9 4-methyl-1-phenylpentan-1-one 
• 78-83-1 2-methyl-propan-1-ol 
• 98-86-2 acetophenone 
• 98-85-1 1-Phenylethanol 
• 2527-66-4 2-methyl-1,2-benzisothiazole-3(2H)-one 
• 54705-19-0 2-(benzylthio)-N-methylbenzamide 
• 20054-45-9 N-methyl-2-sulfanylbenzamide 
• 147-93-3 Thiosalicylic acid 
• 54705-26-9 ortho-[(N-methyl)carbamoyl]phenyl benzyl sulfoxide 
• 107-82-4 i-pentyl bromide 

Downstream Products

• 54624-34-9 (4-methylpent-1-en-1-yl)benzene 
• 2050-07-9 4-methyl-1-phenylpentan-1-one 

Relevant articles and documents

Regioselective Vinylation of Remote Unactivated C(sp3)?H Bonds: Access to Complex Fluoroalkylated Alkenes

Regioselective incorporation of a particular functional group into aliphatic sites by direct activation of unreactive C?H bonds is of great synthetic value. Despite advances in radical-mediated functionalization of C(sp3)?H bonds by a hydrogen-atom transfer process, the site-selective vinylation of remote C(sp3)?H bonds still remains underexplored. Reported herein is a new protocol for the regioselective vinylation of unactivated C(sp3)?H bonds. The remote C(sp3)?H activation is promoted by a C-centered radical instead of the commonly used N and O radicals. The reaction possesses high product diversity and synthetic efficiency, furnishing a plethora of synthetically valuable E alkenes bearing tri-/di-/mono-fluoromethyl and perfluoroalkyl groups.

An umpolung sulfoxide reagent for use as a functionalized benzyl carbanion equivalent

N-Methyl ortho-carbamoylaryl benzyl sulfoxides can be used as synthetic equivalents for α-hydroxy, α-chloro, and α-acetammido benzyl carbanions by means of a two-step sequence involving highly diastereoselective α-C-alkylation with alkyl halides followed by displacement of the sulfinyl residue (which can be recovered and recycled) by a hydroxyl, a chlorine or an acetamido, respectively, under non-oxidative Pummerer conditions. The scope and limits of the method, including a stereoselective version of the reaction, as well as the mechanism of the process are discussed in detail.

RuCl2(DMSO)4 catalyzes the β-alkylation of secondary alcohols with primary alcohols through a hydrogen autotransfer process

The electrophilic β-alkylation of secondary alcohols with primary alcohols is accomplished by a hydrogen autotransfer process catalyzed by RuCl2(DMSO)4. The reaction can produce either simple alkylated secondary alcohols or α,β-unsaturated ketones with good to excellent results just by choosing the appropriate starting secondary alcohol (methyl or longer chain secondary alcohol, respectively), as well as quinolines (by using 2-aminobenzyl alcohol).