288574-78-7

Basic information

• Product Name: ZINPYR-1
• Synonyms: ZINPYR-1;9-(O-CARBOXYPHENYL)-2,7-DICHLORO-4,5-BIS[BIS(2-PYRIDYLMETHYL)AMINOMETHYL]-6-HYDROXY-3-XANTHENONE;9-(2-CARBOXYPHENYL)-2,7-DICHLORO-4,5-BIS[DI(2-PYRIDYL)AMINOMETHYL]-6-HYDROXY-3-XANTHANONE;4',5'-BIS[BIS(2-PYRIDYLMETHYL)AMINOMETHYL]-2',7'-DICHLOROFLUORESCEIN;4',5'-Bis[[bis(2-pyridinylmethyl)amino]methyl]-2',7'-dichloro-3',6'-dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one;ZP 1;9-(2-Carboxyphenyl)-2,7-dichloro-4,5-bis[di(2-pyridyl)aminomethyl]-6-hydroxy-3-xanthanone ZINPYR-1;4',5'-Bis[[bis(2-pyridinylMethyl)aMino]Methyl]-2',7'-dichloro-3',6'-dihydroxy-
• CAS NO: 288574-78-7
• Molecular Formula: C46H36Cl2N6O5
• Molecular Weight: 823.72
• Product Categories: Chelating Agents & Ligands;Fluorescent Labels & Indicators;Intermediates & Fine Chemicals;Pharmaceuticals;organic amine
• Mol File: 288574-78-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 185-187°C
• Boiling Point: 931.2°C at 760 mmHg
• Flash Point: 517°C
• Appearance: pink/Powder
• Density: 1.49g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.745
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• PKA: 2.8(at 25℃)
• Stability: Temperature Sensitive; Store at -20°C
• CAS DataBase Reference: ZINPYR-1(CAS DataBase Reference)
• NIST Chemistry Reference: ZINPYR-1(288574-78-7)
• EPA Substance Registry System: ZINPYR-1(288574-78-7)

Safety Data

• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 288574-78-7(Hazardous Substances Data)

Usage

Description

ZINPYR-1, also known as Pink Salmon Solid, is a cell-permeable fluorescent probe that is highly selective for Zinc. It is characterized by its pink salmon solid appearance and exhibits maximum fluorescence emission at a wavelength of 515nm. This unique property makes it a valuable tool for various applications in different industries.

Uses

Used in Research and Diagnostics:
ZINPYR-1 is used as a fluorometric detection agent for the detection of Zn2+ ions. Its high selectivity and sensitivity make it an ideal choice for research and diagnostic applications, particularly in the field of biochemistry and cell biology. It can be employed to study the role of zinc in various biological processes and to detect changes in zinc levels that may indicate certain health conditions or disorders.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, ZINPYR-1 can be used as a component in the development of drugs targeting zinc-related conditions. Its ability to selectively bind to zinc ions can be leveraged to create targeted therapies for conditions such as Wilson's disease, a genetic disorder characterized by excessive copper accumulation in the body due to impaired zinc regulation.
Used in Environmental Monitoring:
ZINPYR-1 can also be utilized in environmental monitoring to detect and quantify zinc levels in various samples, such as water, soil, and air. This can help in assessing the impact of zinc pollution on ecosystems and human health, as well as in monitoring the effectiveness of remediation efforts.
Used in Material Science:
Due to its unique fluorescent properties, ZINPYR-1 can be employed in the field of material science for the development of advanced materials with specific optical or sensing capabilities. It can be incorporated into the design of new materials for applications such as sensors, displays, or other optoelectronic devices.

Reaction

ZINPYR-1 is a new lipophilic, zinc-sensitive, fluorescent dye able to penetrate cell membranes. Excitation and emission wavelengths are in the visible range (lambda>500nm). This property is a clear advantage over other dyes requiring high energy, tissue damaging UV radiation.

InChI:InChI=1/C46H36Cl2N6O5/c47-39-21-35-41(33-15-1-2-16-34(33)46(57)58)36-22-40(48)43(56)38(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)45(36)59-44(35)37(42(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30/h1-22,55H,23-28H2,(H,57,58)