288624-81-7

Basic information

• Product Name: [9-(2-bromo-4-isopropyl-phenyl)-8-chloro-2-methyl-9H-purin-6-yl]-butyl-ethyl-amine
• CAS NO: 288624-81-7
• Molecular Weight: 464.836
• Mol File: 288624-81-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [9-(2-bromo-4-isopropyl-phenyl)-8-chloro-2-methyl-9H-purin-6-yl]-butyl-ethyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [9-(2-bromo-4-isopropyl-phenyl)-8-chloro-2-methyl-9H-purin-6-yl]-butyl-ethyl-amine(288624-81-7)
• EPA Substance Registry System: [9-(2-bromo-4-isopropyl-phenyl)-8-chloro-2-methyl-9H-purin-6-yl]-butyl-ethyl-amine(288624-81-7)

Safety Data

• Hazardous Substances Data: 288624-81-7(Hazardous Substances Data)

Upstream product

• 169883-27-6 4-N-<2-bromo-4-(1-methylethyl)phenyl>-6-chloro-2-methylpyrimidine-4,5-diamine 
• 228559-10-2 9-(2-bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amino)-2-methyl-7,9-dihydro-purin-8-one 
• 1194-22-5 2-methyl-4,6-dihydroxypyrimidine 
• 82779-50-8 4,6-dichloro-2-methyl-5-nitropyrimidine 
• 51605-97-1 2-bromo-4-isopropylaniline 

Relevant articles and documents

Purin-8-ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists

A series of purin-8-ones was prepared and discovered to have excellent binding affinity to the CRH-R1 receptor. Structure-activity studies focused on amine side-chain optimization, urea substitution and pyridyl isostere incorporation. Thus, the highly potent purin-8-ones show promise as a new class of potential anxiolytics and/or antidepressants.