288853-63-4 Usage
Description
ROSIGLITAZONE-5-SULFOXY, a metabolite of Rosiglitazone, is a light yellow solid with significant pharmaceutical relevance. It is derived from the parent compound Rosiglitazone, which is a thiazolidinedione drug used for treating type 2 diabetes. The presence of the sulfoxyl group in ROSIGLITAZONE-5-SULFOXY imparts unique chemical and biological properties, making it a valuable compound for various applications in the pharmaceutical and medical fields.
Uses
Used in Pharmaceutical Industry:
ROSIGLITAZONE-5-SULFOXY is used as an active pharmaceutical ingredient (API) for the development of medications targeting type 2 diabetes. As a metabolite of Rosiglitazone, it contributes to the overall therapeutic effect of the drug, helping to improve insulin sensitivity and regulate blood sugar levels in patients.
Used in Research and Development:
In the field of medical research, ROSIGLITAZONE-5-SULFOXY serves as a crucial compound for studying the mechanisms of action, pharmacokinetics, and pharmacodynamics of Rosiglitazone. This knowledge aids in the optimization of drug formulations, understanding drug interactions, and developing new therapeutic strategies for diabetes management.
Used in Quality Control and Standardization:
ROSIGLITAZONE-5-SULFOXY is utilized as a reference standard in the quality control and standardization of Rosiglitazone-containing pharmaceutical products. It ensures the accuracy, precision, and reliability of analytical methods used in the quantification and assessment of Rosiglitazone in various dosage forms.
Used in Drug Metabolism Studies:
As a metabolite of Rosiglitazone, ROSIGLITAZONE-5-SULFOXY plays a vital role in drug metabolism studies. It helps researchers understand the metabolic pathways, enzyme interactions, and elimination processes of Rosiglitazone in the human body, which is essential for predicting drug response, optimizing dosing regimens, and minimizing adverse effects.
Check Digit Verification of cas no
The CAS Registry Mumber 288853-63-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,8,8,5 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 288853-63:
(8*2)+(7*8)+(6*8)+(5*8)+(4*5)+(3*3)+(2*6)+(1*3)=204
204 % 10 = 4
So 288853-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C18H19N3O7S2/c1-21(16-7-6-14(11-19-16)28-30(24,25)26)8-9-27-13-4-2-12(3-5-13)10-15-17(22)20-18(23)29-15/h2-7,11,15H,8-10H2,1H3,(H,20,22,23)(H,24,25,26)
