28910-99-8 Usage
Description
Nitrazolam is a novel benzodiazepine, which is a central nervous system depressant. It has been synthesized and its activity has been documented in the literature. Nitrazolam is structurally similar to traditional benzodiazepines like nitrazepam and alprazolam, as well as other novel benzodiazepines such as flunitrazolam and clonazelam. It has been associated with adverse events, including deaths, due to its appearance on the novel and illicit drug markets.
Uses
Used in Pharmaceutical Industry:
Nitrazolam is used as a central nervous system depressant for its sedative and anxiolytic properties. It is similar to other benzodiazepines, which are commonly prescribed for the treatment of anxiety, insomnia, and other conditions related to the central nervous system.
Used in Research and Development:
Nitrazolam is used as a research compound for studying the effects of benzodiazepines on the central nervous system. Its structural similarity to other benzodiazepines makes it a valuable tool for understanding the mechanisms of action and potential risks associated with this class of drugs.
Used in Illicit Drug Market:
Unfortunately, Nitrazolam has also found its way into the novel and illicit drug markets, where it is used as a recreational substance. Its sedative and anxiolytic effects make it appealing to some users, but it also carries significant risks due to its association with adverse events and deaths.
Check Digit Verification of cas no
The CAS Registry Mumber 28910-99-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,9,1 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 28910-99:
(7*2)+(6*8)+(5*9)+(4*1)+(3*0)+(2*9)+(1*9)=138
138 % 10 = 8
So 28910-99-8 is a valid CAS Registry Number.
28910-99-8Relevant articles and documents
Benzodiazepine derivatives
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, (2008/06/13)
Benzodiazepine derivatives of the general formula STR1 where R1 is hydrogen or a hydrocarbon residue of 1-8 carbon atoms, R2 is hydrogen or lower alkyl and rings A and B are unsubstituted or substituted by nitro, trifluoromethyl, halogen, lower alkyl or lower alkoxy, the nitrogen atom in the 5-position being unsubstituted or substituted by an oxygen atom, useful as muscle relaxants, anticonvulsants, sedatives and tranquilizing agents, and processes for production thereof. Also provided are novel intermediates of the general formula STR2 where R2 has the above meaning, rings A and B are unsubstituted or substituted as above and the nitrogen atom in the 4-position is unsubstituted or substituted by an oxygen atom.
Animal feed and process
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, (2008/06/13)
An animal feed comprising a compound of the group consisting of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines of the formula: STR1 WHEREIN R is selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms, inclusive, phenyl, benzyl and -COOR' in which R' is alkyl of 1 to 4 carbon atoms, inclusive; wherein R1 is selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms, inclusive; and wherein R2, R3, R4 and R5 are selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms, inclusive, halogen, nitro, cyano, trifluoromethyl, and alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkanoylamino and dialkylamino in which the carbon chain moieties are of 1 to 3 carbon atom, inclusive and their pharmacologically acceptable acid addition salts in combination with a nutrient feed. A process for obtaining increased productivity in meat producing, milk producing, and egg laying animals by feeding the aforementioned compounds in combination with nutrient feeds.
