28917-41-1

Basic information

• Product Name: 1-CHLORO-2-(2-NITROPHENYL)ETHANE
• Synonyms: 1-CHLORO-2-(2-NITROPHENYL)ETHANE
• CAS NO: 28917-41-1
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.61
• Mol File: 28917-41-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-CHLORO-2-(2-NITROPHENYL)ETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-2-(2-NITROPHENYL)ETHANE(28917-41-1)
• EPA Substance Registry System: 1-CHLORO-2-(2-NITROPHENYL)ETHANE(28917-41-1)

Safety Data

• Hazardous Substances Data: 28917-41-1(Hazardous Substances Data)

Usage

Chlorinated derivative of 2-(2-nitrophenyl)ethane

Indicates that the compound is derived from 2-(2-nitrophenyl)ethane by adding a chlorine atom.

Building block in the synthesis of various compounds

Indicates that the compound is commonly used as an intermediate in the production of other chemical compounds.

Pale yellow solid

Indicates the physical appearance of the compound.

Melting point of 64-65 °C

Indicates the temperature range at which the compound changes from a solid to a liquid.

Soluble in organic solvents such as ethanol and ether

Indicates the solvents in which the compound can dissolve.

Hazardous if ingested, inhaled, or absorbed through the skin

Indicates the potential health risks associated with the compound.

Not known to have any specific commercial uses of its own

Indicates that the compound is primarily used as an intermediate in the production of other chemical compounds and does not have any specific commercial uses.

Upstream product

• 622-24-2 2-phenylethyl chloride 
• 15121-84-3 2-nitro-benzeneethanol 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 88-72-2 1-methyl-2-nitrobenzene 
• 60-12-8 2-phenylethanol 

Downstream Products

• 67857-98-1 <2-(o-Nitro-phenyl)aethyl>malonsaeure 
• 3192-07-2 2-(2-nitrophenyl)ethylsulfonyl chloride 
• 552-16-9 ortho-nitrobenzoic acid 
• 215600-56-9 2-(2-Nitro-phenyl)-ethanesulfonic acid (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 215600-60-5 2-(2-Nitro-phenyl)-ethanesulfonic acid (2R,3S,5R)-3-hydroxy-5-{4-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-2-ylmethyl ester 
• 199122-98-0 2-(2-Nitro-phenyl)-ethanesulfonic acid (2R,3S,5R)-3-hydroxy-5-{6-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-purin-9-yl}-tetrahydro-furan-2-ylmethyl ester 
• 215600-73-0 2-(2-Nitro-phenyl)-ethanesulfonic acid (2R,3S,5R)-3-hydroxy-5-{6-[2-(4-nitro-phenyl)-ethoxy]-2-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-purin-9-yl}-tetrahydro-furan-2-ylmethyl ester 
• 67857-97-0 4-(2-nitrophenyl)-n-butyric acid 
• 120-72-9 indole 
• 479500-92-0 1,1'-biindolyl 
• 579-71-5 2-nitrostyrene 

Relevant articles and documents

Reduction of 1-(2-Chloroethyl)-2-nitrobenzene and 1-(2-Bromoethyl)-2- nitrobenzene at carbon cathodes: Electrosynthetic routes to 1-nitro-2- vinylbenzene and 1H -indole

Studies of the electrochemical reductions of 1-(2-chloroethyl)-2- nitrobenzene (1) and 1-(2-bromoethyl)-2-nitrobenzene (2) at carbon cathodes in dimethylformamide (DMF) containing tetramethylammonium tetrafluoroborate (TMABF4) have been undertaken. Cyclic voltammograms for 1 and 2 exhibit three irreversible cathodic peaks, the first of which is attributed to one-electron reduction of the nitro group, and the resulting nitro radical-anion immediately reacts as a base with the adjacent alkyl halide moiety via an E2 elimination to produce 1-nitro-2-vinylbenzene. At a potential corresponding to the first cathodic peak, bulk electrolyses of 1 or 2 in the absence of a proton donor afford 1-nitro-2-vinylbenzene as principal product, along with 1H -indole and a dimeric species. However, when 1 or 2 is electrolyzed in the presence of either phenol or 2,4-pentanedione as a proton source, the only significant product is 1H -indole. A mechanistic picture for the reductions of 1 and 2 is proposed, and a separate examination of the electrochemical behavior of 1-nitro-2-vinylbenzene has been included as part of this work.

Nucleoside derivatives with photolabile protective groups

The invention relates to nucleo-side derivatives with photo-unstable protective groups of the general formula (I) in which R1 is H, NO2, CN, OCH3, halogen, alkyl or alkoxyalkyl with 1 to 4 C atoms, R2 is H, OCH3, R3 is H, F, Cl, Br, NO2 or an aliphatic ac