289469-86-9Relevant articles and documents
Regioselective Radical Arylation of 3-Hydroxypyridines
Fürst, Michael C. D.,Bock, Leonard R.,Heinrich, Markus R.
, p. 5752 - 5758 (2016/07/13)
The titanium(III)-mediated radical arylation of 3-hydroxypyridines was found to proceed with high regioselectivity for the 2-position. Using aryldiazonium chlorides, which were prepared from the corresponding anilines, as aryl radical sources, a range of 3-hydroxy-2-phenylpyridines were obtained in moderate to good yields under simple reaction conditions. Reactions of ortho-carboxylic ester substituted phenyldiazonium salts directly provided tricyclic benzopyranopyridinones.