28955-71-7

Basic information

• Product Name: 4 - nitro - 2(3H) - benzoxazolone
• Synonyms: 4 - nitro - 2(3H) - benzoxazolone;4-Nitro-1,3-benzoxazol-2(3H)-one;4-Nitro-2,3-dihydro-1,3-benzoxazol-2-one;4-Nitro-3H-benzooxazol-2-one;4-Nitrobenzo[d]oxazol-2(3H)-one
• CAS NO: 28955-71-7
• Molecular Formula: C₇H₄N₂O₄
• Molecular Weight: 180.11766
• Mol File: 28955-71-7.mol
• Article Data: 2

Chemical Properties

• Appearance: Yellow solid
• CAS DataBase Reference: 4 - nitro - 2(3H) - benzoxazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 4 - nitro - 2(3H) - benzoxazolone(28955-71-7)
• EPA Substance Registry System: 4 - nitro - 2(3H) - benzoxazolone(28955-71-7)

Safety Data

• Hazardous Substances Data: 28955-71-7(Hazardous Substances Data)

Usage

General Description

4-nitro-2(3H)-benzoxazolone is a chemical compound that has a nitro group attached to a benzoxazolone ring. It is a synthetic intermediate used in the production of pharmaceuticals and agrochemicals. It is a pale yellow solid with a melting point of 128-130°C. 4 - nitro - 2(3H) - benzoxazolone is not considered to be environmentally hazardous, but it should be handled with care due to its potential to cause skin and eye irritation. It is also a flammable solid and should be stored and handled in accordance with proper safety procedures. Overall, 4-nitro-2(3H)-benzoxazolone is an important compound in the synthesis of various chemicals and should be used with caution.

Upstream product

• 6665-98-1 3-nitrobenzene-1,2-diol 
• 530-62-1 1,1'-carbonyldiimidazole 
• 554-84-7 meta-nitrophenol 
• 14235-05-3 3-nitrophenyl chloroformate 

Downstream Products

• 1338064-62-2 1-(4-(trifluoromethyl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-63-3 1-(2-fluoro-4-(trifluoromethyl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-64-4 1-(2-chloro-4-(trifluoromethyl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-65-5 1-(4-fluoro-2-(trifluoromethyl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-66-6 1-(4-chloro-2-(trifluoromethyl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-67-7 1-(2-(dimethylamino)-4-(trifluoromethyl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-68-8 1-(4-(trifluoromethyl)-2-(pyrrolidin-1-yl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-69-9 1-(4-(trifluoromethyl)-2-(piperidin-1-yl)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-70-2 1-(4-(trifluoromethyl)-2-(4-morpholino)benzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-71-3 1-(4-chlorobenzyl)-3-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)urea 
• 1338064-95-1 2-(4-(trifluoromethyl)phenyl)-N-(2,3-dihydro-2-oxobenzo[d]oxazol-4-yl)acetamide 
• 95-55-6 2-amino-phenol 
• 19932-87-7 6-iodobenzo[d]oxazol-2(3H)-one 
• 2373-98-0 3,3'-dihydroxybenzidine 

Relevant articles and documents

Versatile Cp*Co(III)(LX) Catalyst System for Selective Intramolecular C-H Amidation Reactions

Herein, we report the development of a tailored cobalt catalyst system of Cp*Co(III)(LX) toward intramolecular C-H nitrene insertion of azidoformates to afford cyclic carbamates. The cobalt complexes were easy to prepare and bench-stable, thus offering a convenient reaction protocol. The catalytic reactivity was significantly improved by the electronic tuning of the bidentate LX ligands, and the observed regioselectivity was rationalized by the conformational analysis and DFT calculations of the transition states. The superior performance of the newly developed cobalt catalyst system could be broadly applied to both C(sp2)-H and C(sp3)-H carbamation reactions under mild conditions.