289677-65-2

Basic information

• Product Name: 4-[5-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylsulfanylmethyl)-pyridin-3-yl]-benzoic acid methyl ester
• Synonyms: 4-[5-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylsulfanylmethyl)-pyridin-3-yl]-benzoic acid methyl ester
• CAS NO: 289677-65-2
• Molecular Weight: 383.431
• Mol File: 289677-65-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[5-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylsulfanylmethyl)-pyridin-3-yl]-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylsulfanylmethyl)-pyridin-3-yl]-benzoic acid methyl ester(289677-65-2)
• EPA Substance Registry System: 4-[5-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylsulfanylmethyl)-pyridin-3-yl]-benzoic acid methyl ester(289677-65-2)

Safety Data

• Hazardous Substances Data: 289677-65-2(Hazardous Substances Data)

Upstream product

• 289677-34-5 methyl 4-[5-[[[(1,1-dimethylethyl)silyl]oxy]methyl]-3-pyridinyl]benzoate 
• 289677-63-0 methyl 4-[5-(acetylthio)methyl-3-pyridinyl]benzoate 
• 289677-35-6 methyl 4-[5-hydroxymethyl-3-pyridinyl]benzoate 
• 289677-36-7 methyl 4-[5-chloromethyl-3-pyridinyl]benzoate 
• 152351-91-2 3-bromo-5-(tert-butyldimethylsilanyloxymethyl)pyridine 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 6312-72-7 5-bromo-2,6-diamino-4(3H)-pyrimidinone 
• 289677-64-1 methyl 4-[5-mercaptomethyl-3-pyridinyl]benzoate 

Downstream Products

• 289677-67-4 di-tert-butyl N-{4-[5-[(2,4-diamino-6(1H)-pyrimidinon-5-yl)thiomethyl]-3-pyridinyl]benzoyl}-L-glutamate 
• 289677-66-3 4-[5-(2,4-diamino-6-oxo-1,6-dihydro-pyrimidin-5-ylsulfanylmethyl)-pyridin-3-yl]-benzoic acid 

Relevant articles and documents

Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase

The synthesis and evaluation of a series of conformationally restricted analogues of 10-formyl-tetrahydrofolate as potential inhibitors of glycinamide ribonucleotide transformylase (GAR Tfase) or aminoimidazole carboxamide transformylase (AICAR Tfase) are reported. (C) 2000 Elsevier Science Ltd.