29020-78-8 Usage
Description
(1Z)-4-hydroxy-3-methylnaphthalene-1,2-dione 1-thiosemicarbazone is a thiosemicarbazone derivative derived from naphthalene, featuring both hydroxy and methyl functional groups attached to the naphthalene ring. This chemical compound is recognized for its potential biological activities, such as antitumor and antiviral properties, and holds promise for further research and development in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
(1Z)-4-hydroxy-3-methylnaphthalene-1,2-dione 1-thiosemicarbazone is used as a potential therapeutic agent for its antitumor properties, targeting cancer treatment by leveraging its ability to interact with biological systems at the molecular level.
Used in Antiviral Applications:
In the field of antiviral research, (1Z)-4-hydroxy-3-methylnaphthalene-1,2-dione 1-thiosemicarbazone is utilized for its potential to combat viral infections, providing a foundation for the development of new antiviral medications.
Used in Medicinal Chemistry Research:
(1Z)-4-hydroxy-3-methylnaphthalene-1,2-dione 1-thiosemicarbazone serves as a promising candidate for further exploration in medicinal chemistry, where its chemical structure and reactivity are studied to understand its mechanisms of action and to potentially synthesize new derivatives with enhanced therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 29020-78-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,0,2 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 29020-78:
(7*2)+(6*9)+(5*0)+(4*2)+(3*0)+(2*7)+(1*8)=98
98 % 10 = 8
So 29020-78-8 is a valid CAS Registry Number.
29020-78-8Relevant articles and documents
Synthesis and biological evaluation of novel naphthoquinone derivatives as potential anticancer and antimicrobial agents.
Habib, Nargues S,Mahran, Mona A
, p. 299 - 307 (2007/10/03)
Four novel series of 1,4-naphthoquinone derivatives namely 2,3-disubstiuted 4-[(benzothiazol-2-yl)hydrazono]-1,4-dihydronaphthalen-1-one 4a-c, N1-(2,3-disubstituted-4-oxo-1,4-dihydronaphthalen-1-ylidene)-N2-(benzotriazol-1-yl)acetic acid hydrazide 5a-c, 2,3-disubstituted 4-[(5-aryl-2,3-dihyrothiazol-2-ylidene)hydrazono]-1,4-dihydronaphthalen-1-one 7a-c, and 3-methyl-2-substituted carbamoyl or thiocarbamoyl-hydrazinocarbonylmethylthio-1,4-dihydronaphthalene-1,4-dione 9a-c were synthesized. Three of the new compounds were chosen by NCI to be evaluated as anticancer agents and they showed promising activity. All the prepared compounds were tested as antimicrobial agents.