2903-12-0

Basic information

• Product Name: [1,1'-bicyclohexyl]-1-ol
• Synonyms: [1,1'-bicyclohexyl]-1-ol;1,1'-Bicyclohexan-1-ol
• CAS NO: 2903-12-0
• Molecular Formula: C₁₂H₂₂O
• Molecular Weight: 182.30248
• EINECS: 220-799-1
• Mol File: 2903-12-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 276.7°Cat760mmHg
• Flash Point: 115.4°C
• Appearance: /
• Density: 1.001g/cm³
• CAS DataBase Reference: [1,1'-bicyclohexyl]-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-bicyclohexyl]-1-ol(2903-12-0)
• EPA Substance Registry System: [1,1'-bicyclohexyl]-1-ol(2903-12-0)

Safety Data

• Hazardous Substances Data: 2903-12-0(Hazardous Substances Data)

Usage

Description

[1,1'-Bicyclohexyl]-1-ol, with the molecular formula C12H22O, is a white crystalline solid that features a unique structure with two fused cyclohexane rings. This chemical compound is utilized in the synthesis of various organic compounds and has found applications in the production of pharmaceuticals and chiral ligands for catalytic reactions. Additionally, it serves as a fragrance ingredient in the perfumery and cosmetics industries.

Uses

Used in Organic Synthesis:
[1,1'-Bicyclohexyl]-1-ol is used as a key intermediate in the synthesis of various organic compounds, contributing to the development of new chemical entities and materials.
Used in Pharmaceutical Production:
[1,1'-Bicyclohexyl]-1-ol is employed as a building block in the production of pharmaceuticals, playing a crucial role in the creation of novel drugs and therapeutic agents.
Used in Chiral Ligand Synthesis:
[1,1'-Bicyclohexyl]-1-ol is used as a component in the synthesis of chiral ligands, which are essential for catalytic reactions in the pharmaceutical and chemical industries, enabling the production of enantiomerically pure compounds.
Used in Fragrance Industry:
In the perfumery and cosmetics sectors, [1,1'-Bicyclohexyl]-1-ol is used as a fragrance ingredient, adding unique scents and enhancing the sensory experience of consumer products.

Upstream product

• 22515-99-7 1-(1-Cyclohexenyl)cyclohexan-1-ol 
• 6400-54-0 bicyclohexyl-1-ylamine 
• 931-51-1 cyclohexylmagnesiumchloride 
• 108-94-1 cyclohexanone 
• 92-51-3 cyclohexylcyclohexane 
• 108-85-0 1-bromocyclohexane 
• 201230-82-2 carbon monoxide 
• 38050-70-3 B-methoxyborinane 
• 110-83-8 cyclohexene 
• 931-52-2 cyclohexylmagnesium iodide 
• 90334-41-1 N-Cyclohexylidene-N'-trityl-hydrazine 
• 90334-44-4 N-Cyclohexylidene-N'-(diphenyl-pyridin-4-yl-methyl)-hydrazine 
• 4233-18-5 bicyclohexylidene 
• 84114-87-4 1-(Cyclohex-1-enyl)cyclohex-1-yl Hydroperoxide 

Downstream Products

• 3282-54-0 1-cyclohexyl-1-cyclohexene 
• 100452-55-9 7-cyclohexyl-3,4,5,6-tetrahydro-2H-azepine 
• 20606-25-1 6-cyclohexyl-6-oxohexanoic acid 
• 60263-54-9 1-cyclohexylcyclohexane-1-carboxylic acid 
• 39257-00-6 1-cyclohexylhex-5-en-1-one 
• 108-94-1 cyclohexanone 

Relevant articles and documents

RUTHENIUM COMPLEX AND PRODUCTION METHOD THEREOF, CATALYST, AND PRODUCTION METHOD OF OXYGEN-CONTAINING COMPOUND

PROBLEM TO BE SOLVED: To provide a ruthenium complex that is particularly useful as a catalyst for oxidizing a substrate having a carbon-hydrogen bond. SOLUTION: The ruthenium complex represented by the general formula (i) or a cis conformer thereof is provided. In the general formula (i), R1 represents H, a phenyl group or a substituted phenyl group; R2 represents H, a phenyl group or an alkyl group; L1 represents halogen or water molecule; L2 represents triphenylphosphine, pyridine, imidazole or dimethylsulfoxide; X represents halogen; and n represents 1 or 2. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPO&INPIT

Organocalcium Chemistry: Preparation and Reactions of Highly Reactive Calcium

A highly reactive form of calcium was prepared by the reduction of Ca(II) salts with preformed lithium biphenylide.Remarkably, this activated calcium undergoes oxidative addition to organic bromides, chlorides, or even fluorides to form the organocalcium reagents under very mild conditions in high yields.The resulting organocalcium compounds undergo Grignard-type reactions.Transmetalation with Cu(I) salts forms calcium cuprate reagents which undergo a variety of cross-coupling reactions.The activated calcium reacts with 1,3-dienes to yield the corresponding 2-butene-1,4-diylcalcium complexes.These bis-organocalcium reagents can undergo dialkylation reactions with α,ω-alkylene dihalides and dichlorosilanes to form the corresponding 3-, 5-, and 6-membered ring derivatives.Significantly, these reactions are highly stereospecific and regioselective.

Azo Anions in Synthesis. Use of Trityl- and Diphenyl-4-pyridylmethyl-hydrazones for Reductive C-C Bond Formation from Aldehydes and Ketones

The lithium salts for trityl- and diphenyl-4-pyridylmethyl-hydrazones of both aldehydes and ketones react with electrophiles (alkyl halides, aldehydes, and ketones) at low temperature to form C-trapped azo compounds; these intermediates decompose homolytically with loss of nitrogen below room temperature and can be diverted in a synthetically useful way to alkanes, or alkenes, or alcohols.