291751-47-8

Basic information

• Product Name: (1R,2R,3S,4S,5R)-3α-hydroxy-2β-(p-methoxybenzyloxy)-4β-methyl-8-oxabicyclo[3.2.1]oct-6-en
• Synonyms: (1R,2R,3S,4S,5R)-3α-hydroxy-2β-(p-methoxybenzyloxy)-4β-methyl-8-oxabicyclo[3.2.1]oct-6-en
• CAS NO: 291751-47-8
• Molecular Weight: 276.332
• Mol File: 291751-47-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R,3S,4S,5R)-3α-hydroxy-2β-(p-methoxybenzyloxy)-4β-methyl-8-oxabicyclo[3.2.1]oct-6-en(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3S,4S,5R)-3α-hydroxy-2β-(p-methoxybenzyloxy)-4β-methyl-8-oxabicyclo[3.2.1]oct-6-en(291751-47-8)
• EPA Substance Registry System: (1R,2R,3S,4S,5R)-3α-hydroxy-2β-(p-methoxybenzyloxy)-4β-methyl-8-oxabicyclo[3.2.1]oct-6-en(291751-47-8)

Safety Data

• Hazardous Substances Data: 291751-47-8(Hazardous Substances Data)

Upstream product

• 291751-46-7 (+)-(1R,2R,4S,5R)-2β-(p-methoxybenzyloxy)-4β-methyl-8-oxabicyclo[3.2.1]oct-6-en-3-one 
• 40458-77-3 meso-8-oxabicyclo[3.2.1]oct-6-en-3-one 
• 105-13-5 4-Methoxybenzyl alcohol 
• 291751-45-6 (+)-(1R,2R,4S,5R)-2β-(tert-butyldimethylsilyloxy)-4-methyl-8-oxabicyclo[3.2.1]oct-6-en-3-one 
• 291751-43-4 (+)-(1R,5R)-3-(triethylsiloxy)-8-oxabicyclo[3.2.1]octa-2,6-diene 
• 291751-44-5 (-)-(1R,2R,5R)-2β-(tert-butyldimethylsilyloxy)-8-oxabicyclo[3.2.1]oct-6-en-3-one 
• 152139-49-6 (-)-(1R,2R,5R)-2β-hydroxy-8-oxabicyclo[3.2.1]oct-6-en-3-one 

Downstream Products

• 291751-48-9 (+)-(1R,2R,3S,4S,5R)-2β-(p-methoxybenzyloxy)-4β-methyl-3α-(triisopropylsilyloxy)-8-oxabicyclo[3.2.1]oct-6-ene 

Relevant articles and documents

Synthesis of the C38-C44 segment of altohyrtin A - with an addendum on the preparation of 8-oxabicyclo[3,2.1]oct-6-en-3-one

The densely funtionalized C38-C44 segment F of altohyrtin A with its five contiguous stereogenic centers was prepared in 10 steps and in 28% overall yield (two steps per stereogenic center), from 8- oxabicyclo[3.2.1]oct-6-en-3-one as a template. The preparation of the title compound 1, m.p. 38 °C, is described on a 0.5 m scale in a three-step-two- stage reaction from acetone anti furan. The oxacycle was stored without change at room temperature.