291753-79-2Relevant articles and documents
Regioselective conversion of primary alcohols into iodides in unprotected methyl furanosides and pyranosides
Skaanderup, Philip R.,Poulsen, Carina Storm,Hyldtoft, Lene,Jorgensen, Malene R.,Madsen, Robert
, p. 1721 - 1727 (2002)
Two methods are described for the regioselective displacement of the primary hydroxy group in methyl glycosides with iodide. The first method is a modification of a literature procedure employing triphenylphosphine and iodine, where purification has been
Chiron approach to the total synthesis of Amaryllidaceae alkaloid (+)-lycoricidine
Saidhareddy, Puli,Shaw, Arun K.
, p. 6773 - 6779 (2017/10/30)
A highly stereoselective total synthesis of Amaryllidaceae alkaloid starting from α-D-galactopyranoside has been described. The salient features of this total synthesis are Ferrier carbocyclization reaction for the synthesis of ring A and Suzuki Miyaura c
Stable analogues of nojirimycin-synthesis and biological evaluation of nojiristegine and manno-nojiristegine
Viuff, Agnete H.,Besenbacher, Louise M.,Kamori, Akiko,Jensen, Mikkel T.,Kilian, Mogens,Kato, Atsushi,Jensen, Henrik H.
, p. 9637 - 9658 (2015/09/28)
Two novel iminosugars called nojiristegines, being structural hybrids between nor-tropane alkaloid calystegine and nojirimycins, have been synthesised and found to be stable molecules despite the presence of a hemiaminal functionality. The synthesised iminosugars were evaluated against a panel of glycosidases and the best inhibition (IC50), found against α-glucosidases, was in the micromolar region. The compounds were also evaluated as potential antibiotics but no useful level of activity was observed.