29182-94-3

Basic information

• Product Name: 2-BROMO-N-(3-METHOXY-PHENYL)-ACETAMIDE
• Synonyms: CHEMBRDG-BB 4023677;2-BROMO-N-(3-METHOXY-PHENYL)-ACETAMIDE;AKOS BB/0144;AKOS BBB/496;acetamide, 2-bromo-N-(3-methoxyphenyl)-;2-bromo-N-(3-methoxyphenyl)ethanamide
• CAS NO: 29182-94-3
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.09
• Mol File: 29182-94-3.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 384.4°C at 760 mmHg
• Flash Point: 186.3°C
• Appearance: /
• Density: 1.528g/cm³
• Vapor Pressure: 4.11E-06mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: 2-BROMO-N-(3-METHOXY-PHENYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-N-(3-METHOXY-PHENYL)-ACETAMIDE(29182-94-3)
• EPA Substance Registry System: 2-BROMO-N-(3-METHOXY-PHENYL)-ACETAMIDE(29182-94-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 29182-94-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10BrNO2/c1-13-8-4-2-3-7(5-8)11-9(12)6-10/h2-5H,6H2,1H3,(H,11,12)

Upstream product

• 536-90-3 m-Anisidine 
• 598-21-0 2-Bromoacetyl bromide 
• 22118-09-8 2-bromoacetyl chloride 

Downstream Products

• 1019401-16-1 1-[(3-methoxy-phenylcarbamoyl)-methyl]-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 1019400-18-0 C₁₆H₁₉N₃O₄ 
• 892454-36-3 2-[{5-(4-nitrophenyl)-1,3,4-oxadiazole-2-yl}sulphanyl]-N-(3-methoxyphenyl)acetamide 
• 901116-04-9 C₁₆H₁₅N₃O₂S₂ 
• 1582875-93-1 N-(3-methoxyphenyl)-2-[(phenylsulfonyl)(piperidin-1-yl)amino]acetamide 
• 902625-72-3 4-oxo-N-(3-methoxyphenyl)-[1]benzopyrano[4,3-c]pyrazole-1(4H)acetamide 

Relevant articles and documents

Synthesis and Antifungal Activity of New N-Aryl-2-(2-hydroxyphenylamino)ethylenediamine Derivatives

Abstract: In this study, a series of new N-aryl-2-(2-hydroxyphenylamino)ethylenediamine derivatives has beendesigned, synthesized and evaluated for antifungal activity against six selectedspecies of phytopathogenic fungi. Among the products, the most potent compoundhave demonstrated 97.7% inhibitory activity against S.sclerotiorum at the concentration of 50 μg/mL, which is higherthan that of the positive control chlorothalonil.

Design, synthesis, fungicidal activity and molecular docking studies of novel 2-((2-hydroxyphenyl)methylamino)acetamide derivatives

A series of novel 2-hydroxyphenyl substituted aminoacetamides was designed by molecular hybridization of the aminoacetamide scaffold and 2-hydroxyphenyl motif. The target compounds were synthesized and their fungicidal activities were evaluated. Some of the target compounds showed excellent antifungal activities against S. sclerotiorum and P. capsici. Significantly, compounds 5e displayed the most potent activity against S. sclerotiorum with EC50 = 2.89 μg/mL, which was lower than that of commercial chlorothalonil. The systematic studies provided strong confidence that the hydroxyl group and the carbonyl group are crucial for the fungicidal activity. Molecular docking studies suggest that SDH enzyme could be one of the potential action targets of our compounds.

Synthesis and cytotoxicity of thieno[2,3-b]quinoline-2-carboxamide and cycloalkyl[b]thieno[3,2-e]pyridine-2-carboxamide derivatives

Seventy nine derivatives of thieno[2,3-b]quinolines, tetrahydrothieno[2,3-b]quinoline, dihydrocyclopenta[b]thieno[3,2-e]pyridine, cyclohepta[b]thieno[3,2-e]pyridine and hexahydrocycloocta[b]thieno[3,2-e]pyridine were either synthesized or obtained commercially and tested for their antiproliferative activity against HCT116, MDA-MB-468 and MDA-MB-231 human cancer cell lines. The most potent eight compounds were active against all cell lines with IC50 values in the 80–250 nM range. In general hexahydrocycloocta[b]thieno[3,2-e]pyridines were most active with increasing activity observed as larger cycloalkyl rings were fused to the pyridine ring.