2922-74-9

Basic information

• Product Name: 2'-Deoxyadenosine-5'-monophosphate disodium salt
• Synonyms: 2'-DEOXYADENYLIC ACID SODIUM SALT;2'-DEOXYADENOSINE 5'-MONOPHOSPHATE SODIUM SALT;2'-DEOXYADENOSINE 5'-MONOPHOSPHATE DISODIUM SALT;DAMP-NA2;D-AMP SODIUM SALT;DAMP;5'-Adenylic acid, 2'-deoxy-, disodium salt;2''-Deoxyadenosine-5''-monophosphoric acid disodium salt
• CAS NO: 2922-74-9
• Molecular Formula: C10H12N5Na2O6P
• Molecular Weight: 375.19
• EINECS: 220-873-3
• Mol File: 2922-74-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: H2O: 50 mg/mL, clear, colorless
• CAS DataBase Reference: 2'-Deoxyadenosine-5'-monophosphate disodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-Deoxyadenosine-5'-monophosphate disodium salt(2922-74-9)
• EPA Substance Registry System: 2'-Deoxyadenosine-5'-monophosphate disodium salt(2922-74-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 22-26-36-24/25-37/39
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 2922-74-9(Hazardous Substances Data)

Usage

Description

2'-Deoxyadenosine-5'-monophosphate disodium salt, also known as dAMP(Na2), is a nucleic acid AMP derivative found in DNA. It plays a crucial role in studying adenosine-based interactions during DNA synthesis and DNA damage. 2'-Deoxyadenosine-5'-monophosphate disodium salt has the ability to react with chloride ions, forming 2',3'-diacetylpyridine-5'-diphosphate dibasic chloride, which has been demonstrated to inhibit bacterial growth and serve as an antibacterial agent.

Uses

Used in Research and Development:
2'-Deoxyadenosine-5'-monophosphate disodium salt is used as a research compound for studying adenosine-based interactions during DNA synthesis and DNA damage. It helps researchers understand the mechanisms and processes involved in DNA replication and repair, which can be crucial for developing new therapeutic strategies for various genetic disorders and diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2'-Deoxyadenosine-5'-monophosphate disodium salt is used as an active pharmaceutical ingredient (API) for the development of drugs targeting DNA synthesis and repair mechanisms. Its role in understanding adenosine-based interactions can lead to the creation of novel therapeutic agents for treating genetic disorders and cancer.
Used in Antibacterial Applications:
2'-Deoxyadenosine-5'-monophosphate disodium salt is used as an antibacterial agent due to its ability to react with chloride ions and form 2',3'-diacetylpyridine-5'-diphosphate dibasic chloride. 2'-Deoxyadenosine-5'-monophosphate disodium salt has been shown to inhibit bacterial growth, making it a potential candidate for the development of new antibiotics to combat bacterial infections.
Used in Diagnostics:
In the diagnostics industry, 2'-Deoxyadenosine-5'-monophosphate disodium salt can be used as a diagnostic marker or reagent for detecting specific adenosine-based interactions in DNA synthesis and repair. This can help in the early detection of genetic disorders and diseases, enabling timely intervention and treatment.

Downstream Products

• 61286-93-9 8-bromo-2'-deoxy-adenosine 5'-monophosphate