29238-81-1

Basic information

• Product Name: Phosphonic acid, (trichloromethyl)-, dimethyl ester
• CAS NO: 29238-81-1
• Molecular Formula: C3H6Cl3O3P
• Molecular Weight: 227.412
• Mol File: 29238-81-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (trichloromethyl)-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (trichloromethyl)-, dimethyl ester(29238-81-1)
• EPA Substance Registry System: Phosphonic acid, (trichloromethyl)-, dimethyl ester(29238-81-1)

Safety Data

• Hazardous Substances Data: 29238-81-1(Hazardous Substances Data)

Upstream product

• 56-23-5 tetrachloromethane 
• 36198-87-5 dimethyl trimethylsilyl phosphite 
• 1532-72-5 isoquinoline N-oxide 
• 121-45-9 phosphorous acid trimethyl ester 

Downstream Products

• 63074-33-9 Cl₃CP(O)(OSi(CH₃)3)2 
• 74-88-4 methyl iodide 
• 5994-41-2 (trichloromethyl)phosphonic acid 

Relevant articles and documents

Metal-free phosphonation of heteroarene N-oxides with trialkyl phosphite at room temperature

A new protocol is described for the conversion of heteroarene N-oxides to heteroarylphosphonates through in situ activation with bromotrichloromethane. The N-oxides of isoquinoline, quinoline, quinoxaline and 1,10-phenanthroline were fast transformed into the corresponding heteroarylphosphonates in up to 92% yield under mild conditions in the absence of solvent and metal catalysts. The good functional group tolerance, low cost, feasibility of scale up, and wide availability of reagents make this method a prominent complement to the Hirao coupling.