292635-80-4

Basic information

• Product Name: Benzenesulfonamide, N-(4-chloro-1H-indol-7-yl)-4-cyano-
• CAS NO: 292635-80-4
• Molecular Formula: C15H10ClN3O2S
• Molecular Weight: 331.782
• Mol File: 292635-80-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-(4-chloro-1H-indol-7-yl)-4-cyano-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-(4-chloro-1H-indol-7-yl)-4-cyano-(292635-80-4)
• EPA Substance Registry System: Benzenesulfonamide, N-(4-chloro-1H-indol-7-yl)-4-cyano-(292635-80-4)

Safety Data

• Hazardous Substances Data: 292635-80-4(Hazardous Substances Data)

Upstream product

• 126811-29-8 7-bromo-4-chloro-1H-indole 
• 41513-04-6 2-chloro-5-bromonitrobenzene 
• 292636-12-5 4-chloro-7-aminoindole 
• 49584-26-1 p-cyanobenzenesulfonyl chloride 

Relevant articles and documents

A focused compound library of novel N-(7-indolyl)benzenesulfonamides for the discovery of potent cell cycle inhibitors

A series of compounds containing an N-(7-indolyl)benzenesulfonamide pharmacophore was synthesized and evaluated as a potential antitumor agent. Cell cycle analysis with P388 murine leukemia cells revealed that there were two different classes of potent cell cycle inhibitors; one disrupted mitosis and the other caused G1 accumulation. Herein described is the SAR summary of the substituent patterns on this pharmacophore template. (C) 2000 Elsevier Science Ltd. All rights reserved.