2931-65-9

Basic information

• Product Name: 3-[(3S,3aS,5aS,6R,9aS,9bS)-3-hydroxy-3,3a,6-trimethyl-7-oxododecahydro-1H-cyclopenta[a]naphthalen-6-yl]propanoic acid
• CAS NO: 2931-65-9
• Molecular Formula: C₁₉H₃₀O₄
• Molecular Weight: 322.4391
• Mol File: 2931-65-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 480.2°C at 760 mmHg
• Flash Point: 258.3°C
• Density: 1.125g/cm³
• Vapor Pressure: 3.08E-11mmHg at 25°C
• Refractive Index: 1.52
• CAS DataBase Reference: 3-[(3S,3aS,5aS,6R,9aS,9bS)-3-hydroxy-3,3a,6-trimethyl-7-oxododecahydro-1H-cyclopenta[a]naphthalen-6-yl]propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(3S,3aS,5aS,6R,9aS,9bS)-3-hydroxy-3,3a,6-trimethyl-7-oxododecahydro-1H-cyclopenta[a]naphthalen-6-yl]propanoic acid(2931-65-9)
• EPA Substance Registry System: 3-[(3S,3aS,5aS,6R,9aS,9bS)-3-hydroxy-3,3a,6-trimethyl-7-oxododecahydro-1H-cyclopenta[a]naphthalen-6-yl]propanoic acid(2931-65-9)

Safety Data

• Hazardous Substances Data: 2931-65-9(Hazardous Substances Data)

Upstream product

• 58-18-4 17-methyltestosterone 

Downstream Products

• 4424-45-7 17β-hydroxy-17α-methyl-4-oxa-5α-androstane-3-one 

Relevant articles and documents

Development of a commercial process to produce oxandrolone

A manufacturing scale process for the preparation of the anabolic steroid Oxandrolone was developed. Key elements included the following: the bromination of methylandrostanolone with perbromide to give the 2-bromoketone in ca. 80% yield with minimal dehydration, subsequent elimination of the bromide with Li2CO3/LiBr to give the 2-enone in ca. 70% yield with minimal formation of methyltestosterone, and an ozonolysis procedure to give the penultimate intermediate in ca. 90% yield. The overall yield from methylandrostanolone to Oxandrolone using the described process was 45% as compared to the original Searle yield of 8%.