29314-09-8

Basic information

• Product Name: Quinoline, 7-phenyl-
• CAS NO: 29314-09-8
• Molecular Formula: C15H11N
• Molecular Weight: 205.259
• Mol File: 29314-09-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Quinoline, 7-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 7-phenyl-(29314-09-8)
• EPA Substance Registry System: Quinoline, 7-phenyl-(29314-09-8)

Safety Data

• Hazardous Substances Data: 29314-09-8(Hazardous Substances Data)

Upstream product

• 2113-54-4 N-(biphenyl-3-yl)acetamide 
• 56-81-5 glycerol 
• 2243-47-2 3-biphenyl amine 
• 697746-00-2 4-chloro-7-phenylquinoline 
• 851985-81-4 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline 
• 100-58-3 phenylmagnesium bromide 
• 4965-36-0 7-bromoquinoline 
• 98-80-6 phenylboronic acid 
• 612-61-3 7-chloroquinoline 
• 855633-93-1 4-hydroxy-7-phenyl-quinoline-2-carboxylic acid ethyl ester 
• 855633-94-2 4-hydroxy-7-phenyl-quinoline-2-carboxylic acid 
• 178984-29-7 7-phenyl-quinolin-4-ol 

Downstream Products

• 60640-17-7 7-phenyl-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

Highly Enantioselective Direct Synthesis of Endocyclic Vicinal Diamines through Chiral Ru(diamine)-Catalyzed Hydrogenation of 2,2′-Bisquinoline Derivatives

An asymmetric hydrogenation of 2,2′-bisquinoline and bisquinoxaline derivatives, catalyzed by chiral cationic ruthenium diamine complexes, was developed. A broad range of chiral endocyclic vicinal diamines were obtained in high yields with excellent diastereo- and enantioselectivity (up to 93:7 dl/meso and >99 % ee). These chiral diamines could be easily transformed into a new class of chiral N-heterocyclic carbenes (NHCs), which are important but difficult to access.

Chemoselective One-Pot Synthesis of Functionalized Amino-azaheterocycles Enabled by COware

Functionalized bicyclic amino-azaheterocycles are rapidly accessed in a one-pot cross-coupling/reduction sequence enabled by the use of COware. Incompatible reagents are physically separated in a single reaction vessel to effect two chemoselective transformations - Suzuki-Miyaura cross-coupling and heteroarene reduction. The developed method allows access to novel heterocyclic templates, including semisaturated Hedgehog and dual PI3K/mTOR inhibitors, which show enhanced physicochemical properties compared to their unsaturated counterparts.

METHOD OF PREPARING SILYLATIVE-REDUCED N-HETEROCYCLIC COMPOUND USING ORGANOBORON CATALYST

Provided is a method of preparing a silylative-reduced N-heterocyclic compound by reducing an N-heteraromatic compound including a sp2 hybridized nitrogen atom while simultaneously introducing a silyl group into a beta-position with respect to a nitrogen atom of the N-heteroaromatic compound, using a silane compound, in the presence of an organoboron catalyst.