2933-50-8

Basic information

• Product Name: 4H-1,3-Oxazin-2-amine, 5,6-dihydro-N-phenyl-
• CAS NO: 2933-50-8
• Molecular Formula: C10H12N2O
• Molecular Weight: 176.218
• Mol File: 2933-50-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4H-1,3-Oxazin-2-amine, 5,6-dihydro-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Oxazin-2-amine, 5,6-dihydro-N-phenyl-(2933-50-8)
• EPA Substance Registry System: 4H-1,3-Oxazin-2-amine, 5,6-dihydro-N-phenyl-(2933-50-8)

Safety Data

• Hazardous Substances Data: 2933-50-8(Hazardous Substances Data)

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 80254-04-2 N-(3-aminopropyl)-5,6,8,9-tetrahydro-7-phenyldibenzoacridinium trifluoromethanesulphonate 
• 3420-63-1 N-(3-Chloropropyl)-N'-phenylurea 
• 3420-69-7 azetidine-1-carboxylic acid anilide 

Downstream Products

• 59208-34-3 3,4-dihydro-2H-[1,3]oxazino[3,2-a]benzimidazole 
• 129663-49-6 1-(5,6-Dihydro-4H-[1,3]oxazin-2-yl)-1,3-diphenyl-urea 
• 129663-43-0 2-[(Z)-Phenylimino]-[1,3]oxazinane-3-carboxylic acid phenylamide 

Relevant articles and documents

A convenient method for the synthesis of 2-amino substituted aza-heterocycles from N,N′-disubstituted thioureas using TsCl/NaOH

p-Toluenesulfonyl chloride (TsCl)/NaOH has been introduced as reagent combination for the synthesis of 2-amino-oxa- or 2-amino-thiazolidines from N-(2-hydroxyethyl)-thioureas, but its general application in heterocycle synthesis has not been investigated. In this paper the convenient and efficient synthesis of a variety of 2-amino-substituted 1-aza 3-(aza, oxo or thio) heterocycles of different substitution and ring sizes is described. The application of polymer-supported TsCl facilitates work-up and renders the reaction conditions very suitable for parallel or robot synthesis. Graphical Abstract