293306-83-9

Basic information

• Product Name: 2-(3,4-difluoro-phenyl)-4-phenyl-oxazole
• CAS NO: 293306-83-9
• Molecular Weight: 257.239
• Mol File: 293306-83-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3,4-difluoro-phenyl)-4-phenyl-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-difluoro-phenyl)-4-phenyl-oxazole(293306-83-9)
• EPA Substance Registry System: 2-(3,4-difluoro-phenyl)-4-phenyl-oxazole(293306-83-9)

Safety Data

• Hazardous Substances Data: 293306-83-9(Hazardous Substances Data)

Upstream product

• 85118-04-3 (3,4-difluoro-phenyl)-amide 
• 70-11-1 α-bromoacetophenone 

Relevant articles and documents

Substituted oxazole benzenesulfonamides as potent human β3 adrenergic receptor agonists

As a part of our investigation into the development of orally bioavailable β3 adrenergic receptor agonists, we have identified a series of substituted oxazole derivatives that are potent β3 agonists with excellent selectivity against other β receptors. Several of these compounds showed excellent oral bioavailability in dogs. One example, cyclopentylethyloxazole 5f is a potent β3 agonist (EC50 = 14 nM, 84% activation) with 340-fold and 160-fold selectivity over β1 and β2 receptors, respectively, and has 38% oral bioavailability in dogs. (C) 2000 Elsevier Science Ltd. All rights reserved.