294653-01-3

Basic information

• Product Name: methyl 4-(4-fluoroanilino)-4-oxobutanoate
• Synonyms: methyl 4-(4-fluoroanilino)-4-oxobutanoate;methyl 4-[(4-fluorophenyl)amino]-4-oxobutanoate
• CAS NO: 294653-01-3
• Molecular Formula: C11H12FNO3
• Molecular Weight: 225.2162832
• Mol File: 294653-01-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 4-(4-fluoroanilino)-4-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(4-fluoroanilino)-4-oxobutanoate(294653-01-3)
• EPA Substance Registry System: methyl 4-(4-fluoroanilino)-4-oxobutanoate(294653-01-3)

Safety Data

• Hazardous Substances Data: 294653-01-3(Hazardous Substances Data)

Upstream product

• 780-05-2 (Z)-4-((4-fluorophenyl)amino)-4-oxobut-2-enoic acid 
• 67-56-1 methanol 
• 6633-22-3 N-(4-fluorophenyl)maleimide 

Relevant articles and documents

First triphenylphosphine promoted reduction of maleimides to succinimides

Triphenylphosphine (TPP) in refluxing methanol effectively reduces maleimides 1a-g to the corresponding succinimides 2a-g in good yields. It was observed that some maleimides obtained from aromatic halogen compounds 1h-j were transformed into the corresponding succinamic acid methyl esters 3a-c by this reaction.