294862-80-9

Basic information

• Product Name: 1-[(2S,3R)-2-benzyloxy-5-(tert-butyldimethylsilyloxy)-3-pentyl]imidazole-4-carboxamide
• Synonyms: 1-[(2S,3R)-2-benzyloxy-5-(tert-butyldimethylsilyloxy)-3-pentyl]imidazole-4-carboxamide
• CAS NO: 294862-80-9
• Molecular Weight: 417.624
• Mol File: 294862-80-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[(2S,3R)-2-benzyloxy-5-(tert-butyldimethylsilyloxy)-3-pentyl]imidazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2S,3R)-2-benzyloxy-5-(tert-butyldimethylsilyloxy)-3-pentyl]imidazole-4-carboxamide(294862-80-9)
• EPA Substance Registry System: 1-[(2S,3R)-2-benzyloxy-5-(tert-butyldimethylsilyloxy)-3-pentyl]imidazole-4-carboxamide(294862-80-9)

Safety Data

• Hazardous Substances Data: 294862-80-9(Hazardous Substances Data)

Upstream product

• 26832-08-6 imidazole-4-carboxamide 
• 700363-47-9 (3S,4S)-4-benzyloxy-1-(tert-butyldimethylsilyloxy)pentan-3-ol 
• 294863-22-2 (-)-(3S,4S)-4-(benzyloxy)-3-(tert-butyldimethylsilyloxy)pentan-1-ol 
• 294862-91-2 (3S,4S)-4-benzyloxypentane-1,3-diol 
• 148409-86-3 methyl (3S,4S)-4-benzyloxy-3-(tert-butyldimethylsilyloxy)pentanoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 335022-98-5 1-[(2S,3R)-2-benzyloxy-5-(2-naphthyloxy)-3-pentyl]imidazole-4-carboxamide 
• 294863-25-5 1-[(2S,3R)-2-benzyloxy-5-methylsulfonyloxy-3-pentyl]imidazole-4-carboxamide 
• 294863-24-4 1-[(2S,3R)-2-benzyloxy-5-hydroxy-3-pentyl]imidazole-4-carboxamide 

Relevant articles and documents

Structure-based design and synthesis of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors

We disclose optimization efforts based on the novel non-nucleoside adenosine deaminase (ADA) inhibitor, 4 (Ki = 680 nM). Structure-based drug design utilizing the crystal structure of the 4/ADA complex led to discovery of 5 (Ki = 11