295365-24-1

Basic information

• Product Name: (2S)-2-phenyl-6-propyl-4-oxo-1,2,3,4-tetrahydropyridine-5-carboxylic acid ethyl ester
• Synonyms: (2S)-2-phenyl-6-propyl-4-oxo-1,2,3,4-tetrahydropyridine-5-carboxylic acid ethyl ester
• CAS NO: 295365-24-1
• Molecular Weight: 287.359
• Mol File: 295365-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S)-2-phenyl-6-propyl-4-oxo-1,2,3,4-tetrahydropyridine-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-2-phenyl-6-propyl-4-oxo-1,2,3,4-tetrahydropyridine-5-carboxylic acid ethyl ester(295365-24-1)
• EPA Substance Registry System: (2S)-2-phenyl-6-propyl-4-oxo-1,2,3,4-tetrahydropyridine-5-carboxylic acid ethyl ester(295365-24-1)

Safety Data

• Hazardous Substances Data: 295365-24-1(Hazardous Substances Data)

Upstream product

• 3249-68-1 ethyl butyroyl acetate 
• 3082-69-7 ethyl (3S)-3-amino-3-phenylpropionate 

Downstream Products

• 295365-27-4 (2S)-2-phenyl-6-propyl-1,2,3,4-tetrahydropiridine-4-one 

Relevant articles and documents

A simple and stereospecfic route to 2,6-disubstituted 4-hydroxypiperidines. Synthesis of dendrobate alkaloid (+)-241D and formal synthesis of (-)-indolizidine 167B.

The condensation of enantiopure beta-amino esters with beta-ketoesters followed by cyclization and decarboxylation afforded 2,3-dihydro-4-pyridones 3, which were selectively hydrogenated to provide 2,6-disubstituted 4-hydroxypiperdines.