29539-18-2

Basic information

• Product Name: 1H-2-Benzopyran, 3,4-dihydro-3-phenyl-
• CAS NO: 29539-18-2
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• Mol File: 29539-18-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran, 3,4-dihydro-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran, 3,4-dihydro-3-phenyl-(29539-18-2)
• EPA Substance Registry System: 1H-2-Benzopyran, 3,4-dihydro-3-phenyl-(29539-18-2)

Safety Data

• Hazardous Substances Data: 29539-18-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 119367-66-7 C₂₂H₂₂N₂O₃S 
• 5773-56-8 1,2-Diphenylethanol 
• 119391-24-1 C₂₂H₂₁N₂O₃S^(1-)*Li⁽¹⁺⁾ 
• 119391-25-2 C₂₂H₂₁N₂O₃S^(1-)*Na⁽¹⁺⁾ 
• 38453-85-9 2-[2-(hydroxymethyl)phenyl]-1-phenylethanol 
• 50-00-0 formaldehyd 
• 100-52-7 benzaldehyde 
• 100-44-7 benzyl chloride 
• 496-14-0 1,3-dihydroisobenzofuran 
• 87-41-2 2-benzofuran-1(3H)-one 
• 119367-90-7 2-<(Benzyloxy)methyl>benzyl alcohol 
• 119367-65-6 2-<(Benzyloxy)methyl>benzaldehyde 
• 119367-89-4 2-<(Benzyloxy)methyl>benzoic acid 

Downstream Products

• 2674-44-4 3-phenyl-isochroman-1-one 
• 153396-48-6 3,4-dihydro-3-phenyl-H-2-benzopyran-1-ol 
• 2881-31-4 2-(2-oxo-2-phenylethyl)benzoic acid 

Relevant articles and documents

Cyclic acetals as precursors of substituted isochromans and naphthoxepines

The reaction of 6,8-dioxabenzocycloheptenes 3 or 8,10-dioxacycloocta[de]naphthalenes 5 [easily prepared from the dibenzylic diols 1 and 4, respectively, and a carbonyl compound] with an excess of lithium and a catalytic amount of DTBB (2.5 mol %) in THF a

Improved procedure for 3,4-dihydro-1H-2-benzopyran ring closure. A general access to 3-substituted isochromanes

A general method for the ring closure of 1-substituted 2-(- hydroxymethyl)-phenylethanols to 3-substituted isochromanes using p-TsOH supported on silica gel is reported.

1,2-Di(lithiomethyl)benzene from Phthalan: Sequential Introduction of Two Different Electrophiles

The reaction of phthalan (1) with an excess of lithium powder and a catalytic amount of DTBB (2.5 mol percent) in THF at 20 deg C followed by treatment with electrophiles (D2O, CO2 and carbonyl compounds) at -78 deg C leads, after hydrolysis, to the corresponding functionalised benzylic alcohols 3a-g.When the lithiation reaction is continued, after the reaction with the first electrophile, and a second electrophile (H2O, D2O and carbonyl compounds) is added, the corresponding disubstituted compounds 6a-q are prepared.Diols 3c-g and 6h,i,l,n and hydroxyacids 6a,c,f,k are easily dehydrated to the corresponding cyclic ethers (7c-f, 8h,i,l,n) or lactones (9a,c,f,k) respectively.Finally, alcohols 6b,d,e give, after acid treatment, the Friedel-Crafts type benzocyclopentenes 10b,d,e.