29576-13-4

Basic information

• Product Name: 2-Butenoic acid, 4-hydroxy-, methyl ester, (E)-
• CAS NO: 29576-13-4
• Molecular Formula: C5H8O3
• Molecular Weight: 116.117
• Mol File: 29576-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 4-hydroxy-, methyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 4-hydroxy-, methyl ester, (E)-(29576-13-4)
• EPA Substance Registry System: 2-Butenoic acid, 4-hydroxy-, methyl ester, (E)-(29576-13-4)

Safety Data

• Hazardous Substances Data: 29576-13-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 107-19-7 propargyl alcohol 

Downstream Products

• 68151-72-4 2c-biphenyl-4-yl-1-isopropyl-6-oxo-(3ar,6ac)-hexahydro-furo[3,4-b]pyrrole-3c-carboxylic acid methyl ester 
• 13865-19-5 4-oxobutanoic acid methyl ester 
• 1117-71-1 methyl-4-bromo-2-butenoate 
• 1061337-31-2 C₁₃H₁₉NO₄ 
• 1061337-35-6 C₁₃H₁₉NO₄ 
• 1061337-20-9 C₁₄H₁₉NO₅ 
• 1061337-25-4 C₁₄H₁₉NO₅ 
• 132055-00-6 (7S,8S,9S)-12,12-Diphenyl-11,13-dioxa-12-sila-tricyclo[7.4.1.0^2,7]tetradec-1-ene-8-carboxylic acid methyl ester 
• 89291-90-7 4-(tert-Butyl-diphenyl-silanyloxy)-3-((2S,5S)-1,4-dibenzyl-2,5-bis-benzyloxy-3,6-dioxo-piperazin-2-yl)-butyric acid methyl ester 
• 145193-28-8 methyl (E)-4-(p-nitrophenyldiazoacetoxy)-2-butenaote 
• 144537-85-9 bis<(E)-3-(methoxycarbonyl)-2-propenyloxy>phenylmethane 
• 174197-88-7 1,1-bis<(E)-3-(methoxycarbonyl)-2-propenyloxy>cyclohexane 
• 192520-06-2 (2E,4E)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-phenylsulfanyl)-2-methyl-penta-2,4-dienoic acid (E)-3-methoxycarbonyl-allyl ester 

Relevant articles and documents

New insights into the alkoxycarbonylation of propargyl alcohol

The challenging carbonylation of propargyl alcohol is effectively catalyzed by Pd(OAc)2 in combination with diphenyl-(6-methyl-pyridin-2-yl)phosphine and methanesulfonic acid. In dichloroethane at 20–50 °C, the reaction affords with almost complete regioselectivity alkyl 2-(hydroxymethyl)acrylates. Turnover frequency numbers (TOF) of up to 450 h?1 can be achieved working at 50 °C, while a maximum turnover number (TON) of about 730 is obtained at 30 °C. The catalyst longevity is limited because the carbonylation product reacts with the phosphorus atom of the ligand to give a quaternary phosphonium salt. This reaction leads to deactivation of the catalyst and eventually to palladium black formation.