29582-15-8

Basic information

• Product Name: 2-p-chlorophenylhydrazono-1-phenylethanone
• Synonyms: 2-p-chlorophenylhydrazono-1-phenylethanone
• CAS NO: 29582-15-8
• Molecular Weight: 258.707
• Mol File: 29582-15-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-p-chlorophenylhydrazono-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-p-chlorophenylhydrazono-1-phenylethanone(29582-15-8)
• EPA Substance Registry System: 2-p-chlorophenylhydrazono-1-phenylethanone(29582-15-8)

Safety Data

• Hazardous Substances Data: 29582-15-8(Hazardous Substances Data)

Upstream product

• 614-20-0 3-oxo-3-phenylpropionic acid 
• 2028-74-2 p-chlorobenzenediazonium chloride 
• 17333-85-6 4-chlorophenyldiazonium salt 

Downstream Products

• 1265802-10-5 3-amino-6-benzoyl-2-p-chlorophenyl-5-phenyl-2,5-dihydropyridazine-4-carbonitrile 
• 1265802-16-1 3-amino-6-benzoyl-2-p-chlorophenyl-5-phenyl-2,5-dihydropyridazine-4-carboxylic acid ethyl ester 
• 7243-00-7 1-phenyl-3-phenylsulfanyl-propane-1,2-dione-2-(4-chloro-phenylhydrazone) 
• 122338-65-2 1,1'-diphenyl-3,3'-piperazine-1,4-diyl-bis-propane-1,2-dione 2,2'-bis-[(4-chloro-phenyl)-hydrazone] 
• 110875-29-1 β-Piperidino-α-(4-chlorphenyl-hydrazono)-propiophenon 

Relevant articles and documents

Improved synthesis of 2-arylhydrazono-3-hydroxy-1-propanones and their utility in efficient synthesis of pyridazine derivatives

Reaction of 2-arylhydrazono-1-phenylethanones 2a-c with formaldehyde either in presence of montmorillonite K10 or by simply stirring in methanol and TEA leads to selective synthesis of 2-arylhydrazono-3-hydroxy-1-phenylpropan-1-one derivatives 3a-c in high yield. Heating 1a with N-phenylmaleimide in DPE/DABCO using microwave irradiation for 5 minutes at 200 °C results in a 73% yield of pyrrolo[3, 4-c]pyridazine 8. Compounds 2a-c react with benzylidenemalononitriles 9a or ethyl 2-cyanocinnamate 9b in refluxing ethanol and piperidine or β-chitosan to yield new pyridazine derivatives 10a-f which are converted into pyridazinones 11a-c upon reflux in acetic/hydrochloric acids mixture. ARKAT-USA, Inc.